AIMC Topic: Histological Techniques

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Cellular community detection for tissue phenotyping in colorectal cancer histology images.

Medical image analysis
Classification of various types of tissue in cancer histology images based on the cellular compositions is an important step towards the development of computational pathology tools for systematic digital profiling of the spatial tumor microenvironme...

Context-Aware Convolutional Neural Network for Grading of Colorectal Cancer Histology Images.

IEEE transactions on medical imaging
Digital histology images are amenable to the application of convolutional neural networks (CNNs) for analysis due to the sheer size of pixel data present in them. CNNs are generally used for representation learning from small image patches (e.g. 224×...

Enabling a Single Deep Learning Model for Accurate Gland Instance Segmentation: A Shape-Aware Adversarial Learning Framework.

IEEE transactions on medical imaging
Segmenting gland instances in histology images is highly challenging as it requires not only detecting glands from a complex background but also separating each individual gland instance with accurate boundary detection. However, due to the boundary ...

Deep Learning-Based Classification of Liver Cancer Histopathology Images Using Only Global Labels.

IEEE journal of biomedical and health informatics
Liver cancer is a leading cause of cancer deaths worldwide due to its high morbidity and mortality. Histopathological image analysis (HIA) is a crucial step in the early diagnosis of liver cancer and is routinely performed manually. However, this pro...

Computer-Aided Diagnosis in Histopathological Images of the Endometrium Using a Convolutional Neural Network and Attention Mechanisms.

IEEE journal of biomedical and health informatics
Uterine cancer (also known as endometrial cancer) can seriously affect the female reproductive system, and histopathological image analysis is the gold standard for diagnosing endometrial cancer. Due to the limited ability to model the complicated re...

Deep Learning-Based Gleason Grading of Prostate Cancer From Histopathology Images-Role of Multiscale Decision Aggregation and Data Augmentation.

IEEE journal of biomedical and health informatics
Visual inspection of histopathology images of stained biopsy tissue by expert pathologists is the standard method for grading of prostate cancer (PCa). However, this process is time-consuming and subject to high inter-observer variability. Machine le...

Hover-Net: Simultaneous segmentation and classification of nuclei in multi-tissue histology images.

Medical image analysis
Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification enables th...

Utilizing supervised machine learning to identify microglia and astrocytes in situ: implications for large-scale image analysis and quantification.

Journal of neuroscience methods
BACKGROUND: The evaluation of histological tissue samples plays a crucial role in deciphering preclinical disease and injury mechanisms. High-resolution images can be obtained quickly however data acquisition are often bottlenecked by manual analysis...

Impact of pre-analytical variables on deep learning accuracy in histopathology.

Histopathology
AIMS: Machine learning (ML) binary classification in diagnostic histopathology is an area of intense investigation. Several assumptions, including training image quality/format and the number of training images required, appear to be similar in many ...

Rapid histology of laryngeal squamous cell carcinoma with deep-learning based stimulated Raman scattering microscopy.

Theranostics
Maximal resection of tumor while preserving the adjacent healthy tissue is particularly important for larynx surgery, hence precise and rapid intraoperative histology of laryngeal tissue is crucial for providing optimal surgical outcomes. We hypothes...