With monoclonal antibodies becoming one of the largest classes of biopharmaceuticals, it is important to have curated data to train computational models that can accelerate their design. Despite the massive amount of mutagenesis data generated on ant...
Early prediction of hematoma expansion (HE) in patients with intracerebral hemorrhage (ICH) is critical for improving clinical outcome and guiding timely interventions. This study focuses on assessing the effectiveness of artificial intelligence (AI)...
Journal of the American Chemical Society
Nov 23, 2025
The HIV-1 envelope glycoprotein (Env) trimer (gp120/gp41) forms the key functional envelope spike and is the target of neutralizing antibodies. The glycoprotein gp41 component mediates the fusion of viral and host cell membranes. The membrane-interac...
Oncology clinical trials play a pivotal role in the development of new therapeutic options; however, their implementation remains an extremely costly and time-consuming process. Artificial intelligence can open new horizons in the design and conduct ...
Nanozymes, defined as nanomaterials exhibiting intrinsic enzyme-like catalytic properties, represent a rapidly expanding interdisciplinary frontier. Since the initial discovery of peroxidase-like nanozymes, a wide variety of nanomaterials have demons...
BACKGROUND: Lung adenocarcinoma (LUAC) patients with micropapillary (MP) and/or solid (S) generally demonstrate a poorer survival prognosis. In the diagnosis and treatment of stage IA LUAC, precisely establishing personalized treatment strategies for...
International journal of health geographics
Nov 22, 2025
BACKGROUND: Mental-health geomatics require reliable ways to convert high-frequency GPS trajectories into meaningful place types that support indicators such as homestay, location entropy, and spatial extent of daily activities. Raw coordinates are t...
Rectal cancer presents complex surgical challenges due to the confined pelvic anatomy. Robotic-assisted surgery has gained prominence for its enhanced precision, dexterity, and ergonomics compared to conventional laparoscopy. This bibliometric analys...
While artificial intelligence (AI) has demonstrated potential in automating clinical trial matching, most existing solutions rely on high-level structured data or oversimplified criteria. This study introduces a framework to structure and analyze eli...
Neurological diseases, such as stroke, are typically deemed refractory because of the adult mammalian brain's poor ability to self-repair and regenerate, resulting in irreparable cellular damage. Neural stem cells (NSCs) have distinct capabilities to...
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