RNA modifications are known to play a critical role in gene regulation and cellular processes. Specifically, N4-acetylcytidine (ac4C) modification has emerged as a significant marker involved in mRNA translation efficiency, stability, and various dis...
O-linked glycosylation is a crucial post-translational modification that regulates protein function and biological processes. Dysregulation of this process is associated with various diseases, underscoring the need to accurately identify O-linked gly...
The surface modification of titanium (Ti) and its alloys is crucial for improving their osteogenic capability, as their bio-inert nature limits effective osseointegration despite their prevalent use in orthopedic implants. However, these modification...
Health policy (Amsterdam, Netherlands)
Feb 1, 2025
The swift progression of AI within the realm of medical devices has precipitated an imperative for stringent regulatory oversight. The United States, the European Union, and China stand as vanguard entities in the regulatory landscape for AI-enhanced...
Endoscopy is widely used to diagnose gastric cancer and has a high diagnostic performance, but it must be performed by a physician, which limits the number of people who can be diagnosed. In contrast, gastric X-rays can be taken by radiographers, thu...
Ophthalmic surgery, lasers & imaging retina
Feb 1, 2025
BACKGROUND AND OBJECTIVE: This study evaluated optometrists' referral patterns for epiretinal membrane (ERM) patients in Ontario, Canada, and their attitudes towards an artificial intelligence (AI) tool for improving referral accuracy. An anonymous o...
BACKGROUND: Controlling re-emerging outbreaks such as COVID-19 is a critical concern to global health. Disease forecasting solutions are extremely beneficial to public health emergency management. This work aims to design and deploy a framework for r...
OBJECTIVE OF THE STUDY: To develop a machine learning algorithm aimed at predicting the presence of a monoclonal (M-) protein when the β-globulin fraction is elevated.
Recent advancements in deep learning have revolutionized the field of drug discovery, with Transformer-based models emerging as powerful tools for molecular design and property prediction. However, the lack of explainability in such models remains a ...
The brain's ability to learn and distinguish rapid sequences of events is essential for timing-dependent tasks, such as those in sports and music. However, the mechanisms underlying this ability remain an active area of research. Here, we present a P...
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