AIMC Topic: Humans

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Screening of Aβ and phosphorylated tau status in the cerebrospinal fluid through machine learning analysis of portable electroencephalography data.

Scientific reports
Diagnosing Alzheimer's disease (AD) through pathological markers is typically costly and invasive. This study aims to find a noninvasive, cost-effective method using portable electroencephalography (EEG) to detect changes in AD-related biomarkers in ...

Development of a LASSO machine learning algorithm-based model for postoperative delirium prediction in hepatectomy patients.

BMC surgery
OBJECTIVE: The objective of this study was to develop and validate a clinically applicable nomogram for predicting the risk of delirium following hepatectomy.

Derivation and validation of a clinical predictive model for longer duration diarrhea among pediatric patients in Kenya using machine learning algorithms.

BMC medical informatics and decision making
BACKGROUND: Despite the adverse health outcomes associated with longer duration diarrhea (LDD), there are currently no clinical decision tools for timely identification and better management of children with increased risk. This study utilizes machin...

High-reward, high-risk technologies? An ethical and legal account of AI development in healthcare.

BMC medical ethics
BACKGROUND: Considering the disruptive potential of AI technology, its current and future impact in healthcare, as well as healthcare professionals' lack of training in how to use it, the paper summarizes how to approach the challenges of AI from an ...

A radiomics and deep learning nomogram developed and validated for predicting no-collapse survival in patients with osteonecrosis after multiple drilling.

BMC medical informatics and decision making
PURPOSE: Identifying patients who may benefit from multiple drilling are crucial. Hence, the purpose of the study is to utilize radiomics and deep learning for predicting no-collapse survival in patients with femoral head osteonecrosis.

Predicting drug combination side effects based on a metapath-based heterogeneous graph neural network.

BMC bioinformatics
In recent years, combined drug screening has played a very important role in modern drug discovery. Generally, synergistic drug combinations are crucial in treatment for many diseases. However, the toxic side effects of drug combinations are probably...

Development of an interpretable machine learning model based on CT radiomics for the prediction of post acute pancreatitis diabetes mellitus.

Scientific reports
This study sought to establish and validate an interpretable CT radiomics-based machine learning model capable of predicting post-acute pancreatitis diabetes mellitus (PPDM-A), providing clinicians with an effective predictive tool to aid patient man...

DeepDrug as an expert guided and AI driven drug repurposing methodology for selecting the lead combination of drugs for Alzheimer's disease.

Scientific reports
Alzheimer's Disease (AD) significantly aggravates human dignity and quality of life. While newly approved amyloid immunotherapy has been reported, effective AD drugs remain to be identified. Here, we propose a novel AI-driven drug-repurposing method,...

Fast and accurate deep learning scans for signatures of natural selection in genomes using FASTER-NN.

Communications biology
Deep learning classification models based on Convolutional Neural Networks (CNNs) are increasingly used in population genetic inference for detecting signatures of natural selection. Prevailing detection methods treat the design of the classifier as ...