AIMC Topic: Humans

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Machine Learning-Based Bioactivity Prediction and Descriptor-Guided Rational Design of Amyloid-β Aggregation Inhibitors.

ACS chemical neuroscience
Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which amyloid-β (Aβ) aggregation plays a pivotal role in its onset and progression. Inhibiting Aβ aggregation is a promising therapeutic strategy; however, its intrinsically diso...

Correlation between atherogenic index of plasma and retinal vessels in the fundus: a cross-sectional study.

European journal of medical research
BACKGROUND: The Atherogenic Index of Plasma (AIP) is a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol (HDL-C) concentrations and is associated with the burden of atherosclerosis. Currently, the non...

A hybrid vision transformer with ensemble CNN framework for cervical cancer diagnosis.

BMC medical informatics and decision making
Cervical cancer is the leading cause of cancer-related deaths among women worldwide, necessitating early and accurate detection methods. This study introduces a hybrid framework utilizing Vision Transformers (ViT) and ensemble learning-based convolut...

Application of artificial intelligence in predicting the results of open-heart surgery: a scoping review.

BMC medical informatics and decision making
PURPOSE: This scoping review aims to synthesize research on artificial intelligence (AI) in predicting open-heart surgery outcomes, evaluating AI model performance, and identifying gaps in data quality, algorithmic bias, and clinical applicability to...

MaskGraphene: an advanced framework for interpretable joint representation for multi-slice, multi-condition spatial transcriptomics.

Genome biology
Recent advances in spatial transcriptomics (ST) highlight the need to integrate multiple slices for joint analysis. A key challenge is generating interpretable embeddings that preserve spatial geometry while correcting batch effects. We present MaskG...

Cracking the code: a head-to-head comparison of expert clinicians and artificial intelligence in diagnosing rare diseases.

Orphanet journal of rare diseases
BACKGROUND: Patients with rare diseases often face prolonged diagnostic journeys due to the low prevalence and diverse clinical presentations of these conditions. In Germany, specialized centers for rare diseases, established at university hospitals,...

Evaluation of the accuracy of semi-autonomous robotic system versus dynamic navigation in completely edentulous implant surgery: an in vitro study.

BMC oral health
BACKGROUND: This study compared the accuracy (defined by trueness and precision) of implant placement between a semi-autonomous robotic system (SARS) and a dynamic navigation system (DNS) in completely edentulous models, evaluating the influence of a...

Multi-Regional deep learning models for identifying dental restorations and prosthesis in panoramic radiographs.

BMC oral health
BACKGROUND: This study introduces a novel deep learning methodology for the automated detection of a wide range of dental prostheses, including crowns, bridges, and implants, as well as various dental treatments such as fillings, root canal therapies...

Predictive variables analysis for the tongue crib treatment of anterior crossbite in mixed dentition.

BMC oral health
OBJECTIVE: This study aimed to identify key prognostic variables and to develop and validate a clinical prediction model for pre-treatment assessment of tongue crib applicability.