AIMC Topic: Humans

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Optimized efficient attention-based network for facial expressions analysis in neurological health care.

Computers in biology and medicine
Facial Expression Analysis (FEA) plays a vital role in diagnosing and treating early-stage neurological disorders (NDs) like Alzheimer's and Parkinson's. Manual FEA is hindered by expertise, time, and training requirements, while automatic methods co...

Machine Learned Classification of Ligand Intrinsic Activities at Human μ-Opioid Receptor.

ACS chemical neuroscience
Opioids are small-molecule agonists of μ-opioid receptor (μOR), while reversal agents such as naloxone are antagonists of μOR. Here, we developed machine learning (ML) models to classify the intrinsic activities of ligands at the human μOR based on t...

Bridging pharmacology and neural networks: A deep dive into neural ordinary differential equations.

CPT: pharmacometrics & systems pharmacology
The advent of machine learning has led to innovative approaches in dealing with clinical data. Among these, Neural Ordinary Differential Equations (Neural ODEs), hybrid models merging mechanistic with deep learning models have shown promise in accura...

Resolution Enhancement of Metabolomic J-Res NMR Spectra Using Deep Learning.

Analytical chemistry
J-Resolved (J-Res) nuclear magnetic resonance (NMR) spectroscopy is pivotal in NMR-based metabolomics, but practitioners face a choice between time-consuming high-resolution (HR) experiments or shorter low-resolution (LR) experiments which exhibit si...

Machine learning to optimize literature screening in medical guideline development.

Systematic reviews
OBJECTIVES: In a time of exponential growth of new evidence supporting clinical decision-making, combined with a labor-intensive process of selecting this evidence, methods are needed to speed up current processes to keep medical guidelines up-to-dat...

YOLO-V5 based deep learning approach for tooth detection and segmentation on pediatric panoramic radiographs in mixed dentition.

BMC medical imaging
OBJECTIVES: In the interpretation of panoramic radiographs (PRs), the identification and numbering of teeth is an important part of the correct diagnosis. This study evaluates the effectiveness of YOLO-v5 in the automatic detection, segmentation, and...

Morphological classification of neurons based on Sugeno fuzzy integration and multi-classifier fusion.

Scientific reports
In order to extract more important morphological features of neuron images and achieve accurate classification of the neuron type, a method is proposed that uses Sugeno fuzzy integral integration of three optimized deep learning models, namely AlexNe...

Geographical targeting of active case finding for tuberculosis in Pakistan using hotspots identified by artificial intelligence software (SPOT-TB): study protocol for a pragmatic stepped wedge cluster randomised control trial.

BMJ open respiratory research
INTRODUCTION: Pakistan has significantly strengthened its capacity for active case finding (ACF) for tuberculosis (TB) that is being implemented at scale in the country. However, yields of ACF have been lower than expected, raising concerns on its ef...

Explainable deep learning and biomechanical modeling for TMJ disorder morphological risk factors.

JCI insight
Clarifying multifactorial musculoskeletal disorder etiologies supports risk analysis, development of targeted prevention, and treatment modalities. Deep learning enables comprehensive risk factor identification through systematic analyses of disease ...

AI as a Medical Device Adverse Event Reporting in Regulatory Databases: Protocol for a Systematic Review.

JMIR research protocols
BACKGROUND: The reporting of adverse events (AEs) relating to medical devices is a long-standing area of concern, with suboptimal reporting due to a range of factors including a failure to recognize the association of AEs with medical devices, lack o...