AIMC Topic: Humans

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Conditional generative adversarial network technology for OFDM system receiver signal detection.

PloS one
In response to the limited detection accuracy of traditional orthogonal frequency division multiplexing systems in complex wireless channel environments, this study first uses conditional generative adversarial networks to construct a single input/ou...

Combining multifaceted aspects of technology innovations through fuzzy clustering of multilayer networks.

PloS one
This study advances a novel multilayer network model to explore the connection between different aspects of Technological Innovation in European Union (EU) countries. We follow a fuzzy clustering approach and consider three variables: Research and De...

Music genre classification with modified residual learning and dual neural network.

PloS one
Music Genre is an abstract property of music that can identify shared traditions and conventions. In the recent past, music genre classification has shown a significant role in MIR that has attracted the research community to draw attention all aroun...

Academic discourse on ChatGPT in social sciences: A topic modeling and sentiment analysis of research article abstracts.

PloS one
The rapid emergence of ChatGPT has sparked extensive academic discourse across multiple fields. This study focuses on such discourse within the social sciences by examining how scholars frame and evaluate ChatGPT through research article abstracts. D...

AI in primary care - a general practitioner's bucket list.

The European journal of general practice
While the development and use of Artificial Intelligence (AI) in health care have literally exploded in recent years, general practitioners (GPs) continue to struggle with a fragmented health care system and complex patients with multiple conditions ...

Accelerated Discovery of : A Potent MALT1 Allosteric Inhibitor for the Treatment of Mature B-Cell Malignancies.

Journal of medicinal chemistry
MALT1 is a key component of the CARD11-BCL10-MALT1 (CBM) complex downstream from BTK on the B-cell receptor signaling pathway. It is a key mediator of NF-κB signaling and considered a potential therapeutic target for several subtypes of non-Hodgkin's...

Mechanistic Basis for GPCR Phosphorylation-Dependent Allosteric Signaling Specificity of β-Arrestin 1 and 2.

Journal of chemical information and modeling
β-Arrestins (βarr1 and βarr2) are key transducers of G protein-coupled receptor (GPCR) signaling, orchestrating both shared and isoform-specific intracellular pathways. Phosphorylation of the receptor C-terminal tail by GPCR kinases encodes regulator...

Ligand Dissociation Pathways from Membrane Receptors Revealed by Weighted Ensemble Simulations.

The journal of physical chemistry. B
G-protein-coupled receptors (GPCRs) are pivotal in cellular signal transduction and serve as key drug targets. Among them, the β-adrenergic receptors (βAR and βAR) regulate cardiovascular function and are activated by endogenous catecholamines, norep...

Neural predictors of hidden, persistent psychological states at work.

Proceedings of the National Academy of Sciences of the United States of America
Common workplace challenges such as feeling overwhelmed, burned out, or disengaged often remain hidden due to fear of judgment or social norms, contributing to rising mental health crises and organizational dysfunction. This study presents a brain-ba...

Identification of lipid metabolism-related signature in nonalcoholic fatty liver: evidences from transcriptomics and single cell RNA-sequencing analysis.

European journal of medical research
BACKGROUND: Considering the complex and close-knit relationship between non-alcoholic fatty liver disease (NAFLD) and the metabolic status, this study aimed to identify lipid metabolism-related genes (LMGs), construct an effective diagnostic model, a...