AIMC Topic: Humans

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The AlphaFold Database of Protein Structures: A Biologist's Guide.

Journal of molecular biology
AlphaFold, the deep learning algorithm developed by DeepMind, recently released the three-dimensional models of the whole human proteome to the scientific community. Here we discuss the advantages, limitations and the still unsolved challenges of the...

Self-paced learning and privileged information based KRR classification algorithm for diagnosis of Parkinson's disease.

Neuroscience letters
Computer aided diagnosis (CAD) methods for Parkinson's disease (PD) can assist clinicians in diagnosis and treatment. Magnetic resonance imaging (MRI) based CAD methods can help reveal structural changes in brain. Classifier is a key component in CAD...

Machine Learning for Urodynamic Detection of Detrusor Overactivity.

Urology
OBJECTIVE: To develop a machine learning algorithm that identifies detrusor overactivity (DO) in Urodynamic Studies (UDS) in the spina bifida population. UDS plays a key role in assessment of neurogenic bladder in patients with spina bifida. Due to s...

Improvement of peripheral nerve visualization using a deep learning-based MR reconstruction algorithm.

Magnetic resonance imaging
OBJECTIVE: To assess a new deep learning-based MR reconstruction method, "DLRecon," for clinical evaluation of peripheral nerves.

Comparing Revo-i and da Vinci in Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Preliminary Propensity Score Analysis of Outcomes.

Journal of endourology
This study aims to compare perioperative and oncologic outcomes between matched cohorts of localized prostate cancer (PCa) operated on by the same surgeon using the da Vinci Si robot and the Revo-i robot. Nonmetastatic PCa patients undergoing Retzi...

Low-value care and excess out-of-pocket expenditure among older adults with incident cancer - A machine learning approach.

Journal of cancer policy
OBJECTIVE: To evaluate the association of low-value care with excess out-of-pocket expenditure among older adults diagnosed with incident breast, prostate, colorectal cancers, and Non-Hodgkin's Lymphoma.

Prediction of genetic alteration of phospholipase C isozymes in brain disorders: Studies with deep learning.

Advances in biological regulation
Genetic mutations leading to the development of various diseases, such as cancer, diabetes, and neurodegenerative disorders, can be attributed to multiple mechanisms and exposure to diverse environments. These disorders further increase gene mutation...

TSSF-hERG: A machine-learning-based hERG potassium channel-specific scoring function for chemical cardiotoxicity prediction.

Toxicology
The human ether-à-go-go-related gene (hERG) encodes the Kv11.1 voltage-gated potassium ion (K) channel that conducts the rapidly activating delayed rectifier current (I) in cardiomyocytes to regulate the repolarization process. Some drugs, as blocker...

Deep learning for neuroimaging-based diagnosis and rehabilitation of Autism Spectrum Disorder: A review.

Computers in biology and medicine
Accurate diagnosis of Autism Spectrum Disorder (ASD) followed by effective rehabilitation is essential for the management of this disorder. Artificial intelligence (AI) techniques can aid physicians to apply automatic diagnosis and rehabilitation pro...

[Artificial intelligence in ex vivo confocal laser scanning microscopy].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
BACKGROUND: Visual data, such as clinical photographs or pictures from imaging examination methods, such as ex vivo confocal laser scanning microscopy (CLSM), are particularly suitable for machine learning techniques.