AIMC Topic: Humans

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Towards pixel-to-pixel deep nucleus detection in microscopy images.

BMC bioinformatics
BACKGROUND: Nucleus is a fundamental task in microscopy image analysis and supports many other quantitative studies such as object counting, segmentation, tracking, etc. Deep neural networks are emerging as a powerful tool for biomedical image comput...

Artificial neural network metamodel for sensitivity analysis in a total hip replacement health economic model.

Expert review of pharmacoeconomics & outcomes research
: Metamodels have been used to approximate complex simulations and have many applications with sensitivity analysis, optimization, etc. However, their use in health economics is very limited. Application of artificial neural network (ANN) with a heal...

Unsupervised Anomaly Detection With LSTM Neural Networks.

IEEE transactions on neural networks and learning systems
We investigate anomaly detection in an unsupervised framework and introduce long short-term memory (LSTM) neural network-based algorithms. In particular, given variable length data sequences, we first pass these sequences through our LSTM-based struc...

Evolutionary Compression of Deep Neural Networks for Biomedical Image Segmentation.

IEEE transactions on neural networks and learning systems
Biomedical image segmentation is lately dominated by deep neural networks (DNNs) due to their surpassing expert-level performance. However, the existing DNN models for biomedical image segmentation are generally highly parameterized, which severely i...

A Multi-Domain Connectome Convolutional Neural Network for Identifying Schizophrenia From EEG Connectivity Patterns.

IEEE journal of biomedical and health informatics
OBJECTIVE: We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently...

Predicting Quality of Overnight Glycaemic Control in Type 1 Diabetes Using Binary Classifiers.

IEEE journal of biomedical and health informatics
In type 1 diabetes management, maintaining nocturnal blood glucose within target range can be challenging. Although semi-automatic systems to modulate insulin pump delivery, such as low-glucose insulin suspension and the artificial pancreas, are star...

Development of an unsupervised machine learning algorithm for the prognostication of walking ability in spinal cord injury patients.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Traumatic spinal cord injury can have a dramatic effect on a patient's life. The degree of neurologic recovery greatly influences a patient's treatment and expected quality of life. This has resulted in the development of machine ...

Big Data and Artificial Intelligence Modeling for Drug Discovery.

Annual review of pharmacology and toxicology
Due to the massive data sets available for drug candidates, modern drug discovery has advanced to the big data era. Central to this shift is the development of artificial intelligence approaches to implementing innovative modeling based on the dynami...

A superpixel-driven deep learning approach for the analysis of dermatological wounds.

Computer methods and programs in biomedicine
BACKGROUND: The image-based identification of distinct tissues within dermatological wounds enhances patients' care since it requires no intrusive evaluations. This manuscript presents an approach, we named QTDU, that combines deep learning models wi...