Journal of bioscience and bioengineering
Jun 4, 2025
Phage display selection has been used for directed evolution of antibody fragments. However, variants with binding affinity cannot be always identified due to undesirable enrichment of target-unrelated variants in the biopanning process. Here, our go...
The relationship between forest growth and natural-anthropogenic drivers remains controversial, and the relative importance of these factors on short-term forest growth at large scales still unclear. This uncertainty hinders the development of effect...
Automatisms are repetitive, semi-ordered movements often observed in focal impaired awareness seizures and, less frequently, in generalized seizures with brief loss of consciousness. This study aims to improve the detection of these automatisms by op...
BACKGROUND: Ultrasound-based bone surface segmentation is crucial in computer-assisted orthopedic surgery. However, ultrasound images have limitations, including a low signal-to-noise ratio, acoustic shadowing, and speckle noise, which make interpret...
Sphingosine kinase 1 (SphK1) plays a pivotal role in cancer progression, metastasis, and chemotherapy resistance, making it a key target for therapeutic interventions in cancer, cardiovascular diseases, and inflammation. Machine learning models, incl...
The quest for solutions to infectious diseases and life-debilitating disease states has been ongoing for centuries now. Natural products researches have revealed bioactive compounds of plant and microbial origin that offer solutions to health conditi...
OBJECTIVE: Major lower extremity amputation for advanced vascular disease involves significant perioperative risks. Although outcome prediction tools could aid in clinical decision-making, they remain limited. To address this, we developed machine le...
is a highly versatile and resilient pathogen that can infect different tissues and rapidly develop resistance to multiple drugs. Ceftazidime-avibactam (CZA) is an antibiotic often used to treat multidrug-resistant infections; however, the knowledge ...
BACKGROUND: Evidence about the health effects of ultrafine particles (UFPs) remains limited, especially due to challenges in estimating exposure in epidemiological studies.
Under the exposome framework, this study examined the relationship between the urban physical environment and leisure-time physical activity during early midlife based on 394 participants (mean age: 37, range 34-40) from the FinnTwin12 cohort, residi...
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