AIMC Topic: Humans

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Framingham Risk Score Prediction at 12 Months in the STANDFIRM Randomized Control Trial.

Journal of the American Heart Association
BACKGROUND: The STANDFIRM (Shared Team Approach Between Nurses and Doctors for Improved Risk Factor Management; ANZCTR registration ACTRN12608000166370) trial was designed to test the effectiveness of chronic disease care management for modifying the...

Genome evolution of Kaposi sarcoma-associated herpesvirus (KSHV).

Journal of virology
UNLABELLED: Kaposi sarcoma (KS) is the most common cancer in people living with HIV (PLWH), particularly in sub-Saharan Africa (SSA), where Kaposi sarcoma herpesvirus (KSHV or human herpesvirus 8 [HHV-8]) is endemic. In KSHV endemic areas, the overal...

Biofabrication of HepG2 Cells-Laden 3D Structures Using Nanocellulose-Reinforced Gelatin-Based Hydrogel Bioinks: Materials Characterization, Cell Viability Assessment, and Metabolomic Analysis.

ACS biomaterials science & engineering
The successful replication of the intricate architecture of human tissues remains a major challenge in the biomedical area. Three-dimensional (3D) bioprinting has emerged as a promising approach for the biofabrication of living tissue analogues, taki...

Prediction of Adeno-Associated Virus Fitness with a Protein Language-Based Machine Learning Model.

Human gene therapy
Adeno-associated virus (AAV)-based therapeutics have the potential to transform the lives of patients by delivering one-time treatments for a variety of diseases. However, a critical challenge to their widespread adoption and distribution is the high...

Enhancing Accuracy of Operative Reports with Automated Artificial Intelligence Analysis of Surgical Video.

Journal of the American College of Surgeons
BACKGROUND: The creation of operative reports is a tedious documentation task that increases administrative burden, which is a potential driver of burnout. Additionally, operative reports are inherently subjective and may contain inaccuracies and inc...

Hyperspectral Imaging and Deep Learning for Quality and Safety Inspection of Fruits and Vegetables: A Review.

Journal of agricultural and food chemistry
Quality inspection of fruits and vegetables linked to food safety monitoring and quality control. Traditional chemical analysis and physical measurement techniques are reliable, they are also time-consuming, costly, and susceptible to environmental a...

Ligand-Based Drug Discovery Leveraging State-of-the-Art Machine Learning Methodologies Exemplified by Cdr1 Inhibitor Prediction.

Journal of chemical information and modeling
Artificial intelligence (AI) is revolutionizing drug discovery with unprecedented speed and efficiency. In computer-aided drug design, structure-based and ligand-based methodologies are the main driving forces for innovation. In cases where no experi...

Topology optimization of random memristors for input-aware dynamic SNN.

Science advances
Machine learning has advanced unprecedentedly, exemplified by GPT-4 and SORA. However, they cannot parallel human brains in efficiency and adaptability due to differences in signal representation, optimization, runtime reconfigurability, and hardware...

Optimizing Immunotherapy: The Synergy of Immune Checkpoint Inhibitors with Artificial Intelligence in Melanoma Treatment.

Biomolecules
Immune checkpoint inhibitors (ICIs) have transformed melanoma treatment; however, predicting patient responses remains a significant challenge. This study reviews the potential of artificial intelligence (AI) to optimize ICI therapy in melanoma by in...

Use of Artificial Intelligence on Imaging and Preoperatory Planning of the Knee Joint: A Scoping Review.

Medicina (Kaunas, Lithuania)
: This scoping review explores the current state of the art of AI-based applications in the field of orthopedics, focusing on its implementation in diagnostic imaging and preoperative planning of knee joint procedures. : The search was carried out us...