BACKGROUND: Pneumonia is a leading cause of death in under five year olds globally. World Health Organization (WHO) pneumonia diagnostic guidelines rely on non-specific clinical findings. Lung auscultation could improve pneumonia diagnosis, but conve...
BACKGROUND: Relating the geographical distribution of intermediate freshwater snail hosts (viz. vectors of schistosomes) to local environmental attributes offers value for understanding the epidemiological landscape of schistosomiasis transmission in...
UNLABELLED: Kaposi sarcoma (KS) is the most common cancer in people living with HIV (PLWH), particularly in sub-Saharan Africa (SSA), where Kaposi sarcoma herpesvirus (KSHV or human herpesvirus 8 [HHV-8]) is endemic. In KSHV endemic areas, the overal...
Cholera, an acute diarrheal disease, is a serious concern in developing and underdeveloped areas. A qualitative understanding of cholera epidemics aims to foresee transmission patterns based on reported data and mechanistic models. The mechanistic mo...
Millions of Africans are on dolutegravir-based antiretroviral therapy (ART), but few detailed descriptions of dolutegravir resistance and its clinical management exist. We reviewed HIV drug resistance (HIVDR) testing application forms submitted betwe...
Most artificial intelligence (AI) research and innovations have concentrated in high-income countries, where imaging data, IT infrastructures and clinical expertise are plentiful. However, slower progress has been made in limited-resource environment...
This study assessed the ethanol and methanol contents of homemade spirit (Kachasu) sold in Blantyre, Malawi. The likelihood of ethanol and methanol toxicity, respectively, was determined through Monte Carlo simulations using reported Kachasu intake v...
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
Nov 8, 2015
BACKGROUND: The use of dried blood spots (DBS) for HIV-1 viral load quantification can greatly improve access to viral monitoring for HIV-infected patients receiving treatment in resource-limited settings.
With the development and decreasing cost of next-generation sequencing technologies, the study of the human microbiome has become a rapid expanding research field, which provides an unprecedented opportunity in various clinical applications such as d...
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