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Hypnotics and Sedatives

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Effects of Midazolam and Midazolam-Butorphanol on Gastrointestinal Transit Time and Motility in Cockatiels ().

Journal of avian medicine and surgery
Positive contrast gastrointestinal (GI) studies are performed frequently in avian medicine to identify GI obstruction, luminal distension, and intracoelomic mass effects. However, repeated manual restraint and radiographic positioning may result in a...

[Effect of dexmedetomidine on emergence agitation after general anesthesia in children undergoing odontotherapy in day-surgery operating room].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
OBJECTIVE: To study the effectiveness of dexmedetomidine used for general anesthesia maintenance in children undergoing odontotherapy in day-surgery operating room in reducing the incidence of emergence agitation (EA).

Pharmacokinetics of dexmedetomidine during analgosedation in ICU patients.

Journal of pharmacokinetics and pharmacodynamics
Dexmedetomidine (DEX) is a fairly new alfa-agonist which has been increasingly used in recent years for analgosedation, mostly because it offers a unique ability of providing both moderate level of sedation and analgesia without respiratory depressio...

Potential EEG biomarkers of sedation doses in intensive care patients unveiled by using a machine learning approach.

Journal of neural engineering
OBJECTIVE: Sedation of neurocritically ill patients is one of the most challenging situation in ICUs. Quantitative knowledge on the sedation effect on brain activity in that complex scenario could help to uncover new markers for sedation assessment. ...

Monitoring the level of hypnosis using a hierarchical SVM system.

Journal of clinical monitoring and computing
Monitoring level of hypnosis is a major ongoing challenge for anesthetists to reduce anesthetic drug consumption, avoiding intraoperative awareness and prolonged recovery. This paper proposes a novel automated method for accurate assessing of the lev...

Inverse reinforcement learning for intelligent mechanical ventilation and sedative dosing in intensive care units.

BMC medical informatics and decision making
BACKGROUND: Reinforcement learning (RL) provides a promising technique to solve complex sequential decision making problems in health care domains. To ensure such applications, an explicit reward function encoding domain knowledge should be specified...

Predicting Deep Hypnotic State From Sleep Brain Rhythms Using Deep Learning: A Data-Repurposing Approach.

Anesthesia and analgesia
BACKGROUND: Brain monitors tracking quantitative brain activities from electroencephalogram (EEG) to predict hypnotic levels have been proposed as a labor-saving alternative to behavioral assessments. Expensive clinical trials are required to validat...

Clinical decision support system, using expert consensus-derived logic and natural language processing, decreased sedation-type order errors for patients undergoing endoscopy.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Determination of appropriate endoscopy sedation strategy is an important preprocedural consideration. To address manual workflow gaps that lead to sedation-type order errors at our institution, we designed and implemented a clinical decisi...