Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Jan 20, 2021
OBJECTIVE: To study if limited frontotemporal electroencephalogram (EEG) can guide sedation changes in highly infectious novel coronavirus disease 2019 (COVID-19) patients receiving neuromuscular blocking agent.
Journal of clinical monitoring and computing
Apr 15, 2019
Monitoring level of hypnosis is a major ongoing challenge for anesthetists to reduce anesthetic drug consumption, avoiding intraoperative awareness and prolonged recovery. This paper proposes a novel automated method for accurate assessing of the lev...
BMC medical informatics and decision making
Apr 9, 2019
BACKGROUND: Reinforcement learning (RL) provides a promising technique to solve complex sequential decision making problems in health care domains. To ensure such applications, an explicit reward function encoding domain knowledge should be specified...
OBJECTIVE: Sedation of neurocritically ill patients is one of the most challenging situation in ICUs. Quantitative knowledge on the sedation effect on brain activity in that complex scenario could help to uncover new markers for sedation assessment. ...
Journal of pharmacokinetics and pharmacodynamics
Dec 30, 2017
Dexmedetomidine (DEX) is a fairly new alfa-agonist which has been increasingly used in recent years for analgosedation, mostly because it offers a unique ability of providing both moderate level of sedation and analgesia without respiratory depressio...
BACKGROUND: We investigated the influence of dexmedetomidine on the emergence agitation of pediatric patients after ophthalmologic operation under general anesthesia using sevoflurane.
INTRODUCTION: We developed a machine learning model to predict whether or not a cochlear implant (CI) candidate will develop effective language skills within 2 years after the CI surgery by using the pre-implant brain fMRI data from the candidate.
To develop and validate an explainable machine learning (ML) tool to help clinicians predict the risk of propofol-associated hypertriglyceridemia in critically ill patients receiving propofol sedation. Patients from 11 intensive care units (ICUs) a...
OBJECTIVE: This study compared the brain function changes in chronic insomnia disorder (CID) before and after treatment by suanzaoren decoction (SZRD) and estazolam, to reveal their effects in cognition improvement, and to explore the potential genet...
PURPOSE OF REVIEW: To summarize recent developments in the understanding of the pharmacology of the hypnotic and opioid drugs, with relevance to target-controlled infusions and newer pharmacokinetic models.
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