Type 2 diabetes mellitus (DM2) is a chronic metabolic disease. Silver nanoparticles (AgNPs) show promise in their treatment. This study assessed the potential of AgNPs as DM2 treatment agent using in vitro, in vivo, and machine learning approaches. M...
The increasing prevalence of type 2 diabetes (T2D) is a significant health concern worldwide. Effective and personalized treatment strategies are essential for improving patient outcomes and reducing healthcare costs. Machine learning (ML) has the po...
BACKGROUND: Diabetes is a global metabolic disease that urgently calls for the development of new and effective therapeutic agents. Anti-diabetic peptides (ADPs) have emerged as a research hotspot due to their therapeutic potential and natural safety...
Journal of diabetes science and technology
Jul 1, 2025
BACKGROUND: Since the discovery of the life-saving hormone insulin in 1921 by Dr Frederick Banting in 1921, there have been many critical discoveries and technical breakthroughs that have enabled people living with type 1 diabetes (T1D) to live longe...
BACKGROUND: The activation of free fatty acid receptor 4 (FFAR4) enhances insulin sensitivity and glucose uptake while mitigating inflammation. It is a promising therapeutic approach for managing type 2 diabetes mellitus (T2DM).
Journal of agricultural and food chemistry
Jun 5, 2025
The lack of suitable chemical research methodologies has hindered the discovery of rational daily diet combinations from large-scale dietary-derived compounds. Three deep learning models based on chemical properties for α-glucosidase inhibitors (AGIs...
BACKGROUND: Diabetes affects millions worldwide. Primary care physicians provide a significant portion of care, and they often struggle with selecting appropriate medications.
Duckweed, a sustainable, protein-rich aquatic plant, has recently emerged as a promising source of bioactive peptides. However, their identification remains limited and challenging in such complex mixtures. Following duckweed hydrolysis with pepsin, ...
BACKGROUND: Medication adherence plays a crucial role in determining the health outcomes of patients, particularly those with chronic conditions like type 2 diabetes. Despite its significance, there is limited evidence regarding the use of machine le...
International journal of molecular sciences
Feb 24, 2025
Diabetes-related cognitive impairment (DCI) is a severe complication of type 2 diabetes mellitus (T2DM), with limited understanding of its molecular mechanisms hindering effective therapeutic development. This study identified SERPINA3 as a potential...
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