AIMC Topic: Influenza Vaccines

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SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses.

Journal of immunology (Baltimore, Md. : 1950)
Machine learning holds considerable promise for understanding complex biological processes such as vaccine responses. Capturing interindividual variability is essential to increase the statistical power necessary for building more accurate predictive...

Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure.

eLife
Optical super-resolution microscopy techniques enable high molecular specificity with high spatial resolution and constitute a set of powerful tools in the investigation of the structure of supramolecular assemblies such as viruses. Here, we report o...

Immunogenicity of Concentrated and Purified Inactivated Avian Influenza Vaccine Formulation.

Archives of Razi Institute
Avian influenza (AI) H9N2 is a low pathogenic virus subtype belonging to Orthomyxoviridae family. Given the prevalence of this subtype as an infectious agent in poultry industry, special attention has been always directed toward the development of va...

Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults.

Clinical nutrition (Edinburgh, Scotland)
BACKGROUND & AIMS: Mortality resulting from influenza (flu) virus infections occurs primarily in the elderly through declining immunity. Studies in mice have suggested beneficial effects of selenium (Se) supplementation on immunity to flu but similar...

Clinical course of H1N1-vaccine-related narcolepsy.

Sleep medicine
OBJECTIVE: To follow and analyze the clinical course and quality of life of Pandemrix H1N1-vaccine-related narcolepsy (pNT1).

Humanoid robotics in health care: An exploration of children's and parents' emotional reactions.

Journal of health psychology
A new non-pharmacological method of distraction was tested with 57 children during their annual flu vaccination. Given children's growing enthusiasm for technological devices, a humanoid robot was programmed to interact with them while a nurse admini...

Optimizing influenza vaccine allocation: A predictive analytics approach for informed public health planning.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
PURPOSE: Excessive purchasing of influenza vaccine can lead to costly overages and waste of resources. Insufficient quantities, however, can jeopardize population health. Our project aimed to use predictive analytics to determine the influenza vaccin...

Extracting postmarketing adverse events from safety reports in the vaccine adverse event reporting system (VAERS) using deep learning.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Automated analysis of vaccine postmarketing surveillance narrative reports is important to understand the progression of rare but severe vaccine adverse events (AEs). This study implemented and evaluated state-of-the-art deep learning algo...

The risk of racial bias while tracking influenza-related content on social media using machine learning.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Machine learning is used to understand and track influenza-related content on social media. Because these systems are used at scale, they have the potential to adversely impact the people they are built to help. In this study, we explore t...

Time series computational prediction of vaccines for influenza A H3N2 with recurrent neural networks.

Journal of bioinformatics and computational biology
Influenza viruses are persistently threatening public health, causing annual epidemics and sporadic pandemics due to rapid viral evolution. Vaccines are used to prevent influenza infections but the composition of the influenza vaccines have to be upd...