AIMC Topic: T-Lymphocyte Subsets

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Blood-Based Immune Profiling Combined with Machine Learning Discriminates Psoriatic Arthritis from Psoriasis Patients.

International journal of molecular sciences Oct 12, 2021
Psoriasis (Pso) is a chronic inflammatory skin disease, and up to 30% of Pso patients develop psoriatic arthritis (PsA), which can lead to irreversible joint damage. Early detection of PsA in Pso patients is crucial for timely treatment but difficult...
Monocytes Psoriasis Diagnosis, Differential Adult Middle Aged ROC Curve T-Lymphocytes, Regulatory T-Lymphocyte Subsets B-Lymphocyte Subsets Receptors, Chemokine Arthritis, Psoriatic Area Under Curve Discriminant Analysis Humans Machine Learning Phenotype Female Aged
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Combination Strategies for Immune-Checkpoint Blockade and Response Prediction by Artificial Intelligence.

International journal of molecular sciences Apr 19, 2020
The therapeutic concept of unleashing a pre-existing immune response against the tumor by the application of immune-checkpoint inhibitors (ICI) has resulted in long-term survival in advanced cancer patient subgroups. However, the majority of patients...
Biomarkers, Tumor Animals Neoplasms Immune Checkpoint Inhibitors Humans Artificial Intelligence T-Lymphocyte Subsets Antineoplastic Agents, Immunological Immunotherapy Combined Modality Therapy Cancer Vaccines Molecular Targeted Therapy Treatment Outcome
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SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses.

Journal of immunology (Baltimore, Md. : 1950) Jun 14, 2019
Machine learning holds considerable promise for understanding complex biological processes such as vaccine responses. Capturing interindividual variability is essential to increase the statistical power necessary for building more accurate predictive...
Data Mining Influenza Vaccines Datasets as Topic CD8-Positive T-Lymphocytes CD4-Positive T-Lymphocytes Influenza, Human T-Lymphocyte Subsets Young Adult Adult Male Adolescent Child Vaccination Machine Learning Algorithms Female Humans
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Indoleamine 2,3-Dioxygenase (IDO) Enzyme Links Innate Immunity and Altered T-Cell Differentiation in Non-ST Segment Elevation Acute Coronary Syndrome.

International journal of molecular sciences Dec 26, 2017
Atherosclerosis is a chronic inflammatory disease characterized by a complex interplay between innate and adaptive immunity. Dendritic cells (DCs) play a key role in T-cell activation and regulation by promoting a tolerogenic environment through the ...
Cell Differentiation Acute Coronary Syndrome T-Lymphocyte Subsets Indoleamine-Pyrrole 2,3,-Dioxygenase Monocytes Immunity, Innate Non-ST Elevated Myocardial Infarction Middle Aged Dendritic Cells Lymphocyte Activation Aged Aged, 80 and over Humans Adult Cells, Cultured Male Female
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Sensitive detection of rare disease-associated cell subsets via representation learning.

Nature communications Apr 6, 2017
Rare cell populations play a pivotal role in the initiation and progression of diseases such as cancer. However, the identification of such subpopulations remains a difficult task. This work describes CellCnn, a representation learning approach to de...
Leukemia Immunologic Memory Humans Neural Networks, Computer Cytomegalovirus Infections Supervised Machine Learning Survival Analysis Rare Diseases Neoplasm, Residual Killer Cells, Natural T-Lymphocyte Subsets Monocytes Signal Transduction Acquired Immunodeficiency Syndrome Cytokines Prognosis Single-Cell Analysis
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Estimating Normal Values of Rare T-Lymphocyte Populations in Peripheral Blood of Healthy Cuban Adults.

MEDICC review Oct 1, 2018
INTRODUCTION Flow cytometry allows immunophenotypic characterization of important lymphocyte subpopulations for diagnosis of diseases such as cancer, autoimmune diseases, immunodeficiencies and some infections. Normal values of rare lymphoid cells in...
Killer Cells, Natural Lymphocyte Count T-Lymphocyte Subsets Sex Factors CD4-CD8 Ratio Cuba Male Aged, 80 and over Age Factors Middle Aged Humans Young Adult CD4 Lymphocyte Count Adolescent Adult Female Reference Values Aged
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