AIMC Topic: International Normalized Ratio

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Identifying Drug-Drug Interactions by Data Mining: A Pilot Study of Warfarin-Associated Drug Interactions.

Circulation. Cardiovascular quality and outcomes Nov 8, 2016
BACKGROUND: Knowledge about drug-drug interactions commonly arises from preclinical trials, from adverse drug reports, or based on knowledge of mechanisms of action. Our aim was to investigate whether drug-drug interactions were discoverable without ...
Blood Coagulation Retrospective Studies Female Warfarin Risk Factors International Normalized Ratio Aged Registries Logistic Models Drug Prescriptions Aged, 80 and over Predictive Value of Tests Administrative Claims, Healthcare Male Humans Anticoagulants Polypharmacy Pilot Projects Machine Learning Drug Interactions Data Mining Atrial Fibrillation
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Abdominal compartment syndrome in traumatic hemorrhagic shock: is there a fluid resuscitation inflection point associated with increased risk?

American journal of surgery Dec 31, 2015
BACKGROUND: The volume of fluid administered during trauma resuscitation correlates with the risk of abdominal compartment syndrome (ACS). The exact volume at which this risk rises is uncertain. We established the inflection point for ACS risk during...
Abdomen United States Treatment Outcome Fluid Therapy International Normalized Ratio Risk Factors Humans Lactates Injury Severity Score Adult Retrospective Studies Shock, Hemorrhagic Compartment Syndromes Male Wounds, Nonpenetrating Length of Stay Female
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The impact of paracentesis flow rate in patients with liver cirrhosis on the development of paracentesis induced circulatory dysfunction.

Clinical and molecular hepatology Dec 24, 2015
BACKGROUND/AIMS: Ascites is a dreadful complication of liver cirrhosis associated with short survival. Large volume paracentesis (LVP) is used to treat tense or refractory ascites. Paracentesis induced circulatory dysfunction (PICD) develops if no pl...
Arteries Sex Factors Shock Paracentesis Middle Aged Blood Pressure Female Logistic Models International Normalized Ratio Aged Enzyme-Linked Immunosorbent Assay Humans Renin Adult Liver Cirrhosis Creatinine Male
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Critical Appraisal on the Role of Warfarin in the Current Era.

The Journal of the Association of Physicians of India Oct 1, 2023
Warfarin has been the most extensively used oral anticoagulant (OAC) in medical settings for over 60 years. Its uses, potential adverse effects, and methods for reversing its effects have been firmly established, rendering it a routine medication in ...
International Normalized Ratio Drug Monitoring Humans Anticoagulants Warfarin
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New artificial intelligence prediction model using serial prothrombin time international normalized ratio measurements in atrial fibrillation patients on vitamin K antagonists: GARFIELD-AF.

European heart journal. Cardiovascular pharmacotherapy Sep 1, 2020
AIMS: Most clinical risk stratification models are based on measurement at a single time-point rather than serial measurements. Artificial intelligence (AI) is able to predict one-dimensional outcomes from multi-dimensional datasets. Using data from ...
Anticoagulants Female Blood Coagulation Reproducibility of Results Vitamin K Time Factors Risk Factors Humans International Normalized Ratio Hemorrhage Treatment Outcome Aged Neural Networks, Computer Prothrombin Time Registries Predictive Value of Tests Drug Monitoring Aged, 80 and over Databases, Factual Drug Therapy, Computer-Assisted Stroke Prospective Studies Male Administration, Oral Risk Assessment Atrial Fibrillation
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A Machine Learning-Based Model to Predict Acute Traumatic Coagulopathy in Trauma Patients Upon Emergency Hospitalization.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis Jan 1, 2020
Acute traumatic coagulopathy (ATC) is an extremely common but silent murderer; this condition presents early after trauma and impacts approximately 30% of severely injured patients who are admitted to emergency departments (EDs). Given that conventio...
Humans Machine Learning Algorithms Female Middle Aged Risk Assessment Emergencies Predictive Value of Tests Hospitalization Adult Male International Normalized Ratio Blood Coagulation Disorders Wounds and Injuries
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Effects of Plasma Transfusion on Perioperative Bleeding Complications: A Machine Learning Approach.

Studies in health technology and informatics Jan 1, 2015
Perioperative bleeding (PB) is associated with increased patient morbidity and mortality, and results in substantial health care resource utilization. To assess bleeding risk, a routine practice in most centers is to use indicators such as elevated v...
Blood Transfusion International Normalized Ratio Pattern Recognition, Automated Reproducibility of Results Risk Factors Sensitivity and Specificity Prevalence Decision Support Systems, Clinical Treatment Outcome Blood Loss, Surgical Humans Machine Learning Electronic Health Records
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