BACKGROUND: Inflammation plays a critical role in ischemic stroke (IS). This study aimed to identify inflammation-related genes and explore potential pharmacological agents for future preclinical validation in IS.
Neurological diseases, such as stroke, are typically deemed refractory because of the adult mammalian brain's poor ability to self-repair and regenerate, resulting in irreparable cellular damage. Neural stem cells (NSCs) have distinct capabilities to...
Journal of neurointerventional surgery
Nov 18, 2025
BACKGROUND: We investigate the association of imaging biomarkers extracted from fully automated body composition analysis (BCA) of computed tomography (CT) angiography images of endovascularly treated acute ischemic stroke (AIS) patients regarding an...
Acute ischemic stroke is a major global health challenge, leading to long-term disability or death without timely intervention. Among neuroimaging modalities, spatio-temporal (4D) computed tomography perfusion (CTP) is widely used to assess cerebral ...
Journal of neuroengineering and rehabilitation
Oct 27, 2025
BACKGROUND: Early prediction of upper limb recovery is important to optimise rehabilitation and inform patients but remains challenging due to inter-individual variability. This study aims to (1) develop and validate a machine learning model to predi...
Ischemic stroke (IS) is an acute neurological disorder causing brain dysfunction, with high mortality and disability. PANoptosis is a synchronized sort of regulated cell demise that combines the characteristics of pyroptosis, apoptosis, and necroptos...
BACKGROUND: The clinical significance and contribution of the lipid profile in atherosclerosis are well established. However, further investigation is needed in stroke patients, particularly regarding apolipoprotein B100 (ApoB100), a novel non-tradit...
BACKGROUND: Sepsis is a severe and frequent complication among ischemic stroke patients during hospitalization. The atherogenic index of plasma (AIP), as metabolism-related markers, are closely linked to inflammation. However, their relationship with...
Journal of neurointerventional surgery
Oct 16, 2025
BACKGROUND: To evaluate the stand-alone efficacy and improvements in diagnostic accuracy of early-career physicians of the artificial intelligence (AI) software to detect large vessel occlusion (LVO) in CT angiography (CTA).
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