AIMC Topic: Kidney Neoplasms
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Regulatory T cells and matrix-producing cancer associated fibroblasts contribute on the immune resistance and progression of prognosis related tumor subtypes in ccRCC.
Scientific reports
Jul 1, 2025
Clear cell renal cell carcinoma (ccRCC) is a prevalent malignant tumor in the field of urology. The effect of cell heterogeneity on the prognosis and reaction to treatment of ccRCC in large populations is still unclear. By analyzing public single cel...
Identification of CXCR4 as a potential preventive gene in clear cell renal cell carcinoma from machine learning and immune analysis.
Scientific reports
Jul 1, 2025
Clear cell renal cell carcinoma (ccRCC) represents a prevalent malignant kidney tumor characterized by high metastatic potential and recurrence rates. Investigations into the molecular mechanisms and therapeutic targets of ccRCC have provided novel d...
Deep learning model for grading carcinoma with Gini-based feature selection and linear production-inspired feature fusion.
Scientific reports
Jul 1, 2025
The most common types of kidneys and liver cancer are renal cell carcinoma (RCC) and hepatic cell carcinoma (HCC), respectively. Accurate grading of these carcinomas is essential for determining the most appropriate treatment strategies, including su...
Radiogenomic correlation of hypoxia-related biomarkers in clear cell renal cell carcinoma.
Journal of cancer research and clinical oncology
Jun 12, 2025
PURPOSE: This study aimed to evaluate radiomic models' ability to predict hypoxia-related biomarker expression in clear cell renal cell carcinoma (ccRCC).
UNIK (Urologic Non-Neoplastic Investigation of Kidneys): a machine learning approach to decode benign lesion.
World journal of urology
Jun 4, 2025
PURPOSE: Predicting the likelihood of benign neoplasia in patients with suspected renal cell carcinoma (RCC) is a cornerstone of presurgical planning. We sought to create and validate U.N.I.K., a machine learning (ML) model capable of predicting beni...
Radiomics-based differentiation of upper urinary tract urothelial and renal cell carcinoma in preoperative computed tomography datasets.
BMC medical imaging
May 30, 2025
BACKGROUND: To investigate a non-invasive radiomics-based machine learning algorithm to differentiate upper urinary tract urothelial carcinoma (UTUC) from renal cell carcinoma (RCC) prior to surgical intervention.
Multiomics in Renal Cell Carcinoma: Current Landscape and Future Directions for Precision Medicine.
Current urology reports
May 26, 2025
PURPOSE OF REVIEW: Renal cell carcinoma (RCC) is a prevalent and increasingly diagnosed malignancy associated with high mortality and recurrence rates. Traditional diagnostic and therapeutic approaches have limitations due to the disease's molecular ...
Tumor grade-titude: XGBoost radiomics paves the way for RCC classification.
European journal of radiology
Apr 29, 2025
This study aimed to develop and evaluate a non-invasive XGBoost-based machine learning model using radiomic features extracted from pre-treatment CT images to differentiate grade 4 renal cell carcinoma (RCC) from lower-grade tumours. A total of 102 R...
Adult
Sensitivity and Specificity
Radiomics
Male
Reproducibility of Results
Aged
Aged, 80 and over
Kidney Neoplasms
Carcinoma, Renal Cell
Boosting Machine Learning Algorithms
Middle Aged
Contrast Media
Neoplasm Grading
Radiographic Image Interpretation, Computer-Assisted
Humans
Machine Learning
Tomography, X-Ray Computed
Female
Predictive Model of Objective Response to Nivolumab Monotherapy for Advanced Renal Cell Carcinoma by Machine Learning Using Genetic and Clinical Data: The SNiP-RCC Study.
JCO clinical cancer informatics
Apr 25, 2025
PURPOSE: Anti-PD-1 antibodies are widely used for cancer treatment, including in advanced renal cell carcinoma (RCC). However, the therapeutic response varies among patients. This study aimed to predict tumor response to nivolumab anti-PD-1 antibody ...
Identifying potential risk genes for clear cell renal cell carcinoma with deep reinforcement learning.
Nature communications
Apr 15, 2025
Clear cell renal cell carcinoma (ccRCC) is the most prevalent type of renal cell carcinoma. However, our understanding of ccRCC risk genes remains limited. This gap in knowledge poses challenges to the effective diagnosis and treatment of ccRCC. To a...
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