BMC medical informatics and decision making
Apr 4, 2019
BACKGROUND: Clinical text classification is an fundamental problem in medical natural language processing. Existing studies have cocnventionally focused on rules or knowledge sources-based feature engineering, but only a limited number of studies hav...
AIM: Six modern PGx assays were compared with the Pharmacogenomics Knowledge Base (PharmGKB) to determine the proportion of the currently known PGx genotypes that are assessed by these assays.
BACKGROUND: Topologically associating domains (TADs) are considered the structural and functional units of the genome. However, there is a lack of an integrated resource for TADs in the literature where researchers can obtain family classifications a...
International journal of environmental research and public health
Mar 8, 2019
The echinococcosis of humans and animals is a chronic helminthic disease caused by the larva of genus tapeworms. It is a globally distributed disease which is an important socioeconomic and public health problem in many low and middle-income countri...
The interactive adjustment of the optimization objectives during the treatment planning process has made it difficult to evaluate the impact of beam quality exclusively in radiotherapy. Without consensus in the published results, the arbitrary select...
Measuring drug-drug similarity is important but challenging. Significant progresses have been made in drugs whose labeled training data is sufficient and available. However, handling data skewness and incompleteness with domain-specific knowledge gra...
PURPOSE: Knowledge-based planning (KBP) clinical implementation necessitates significant upfront effort, even within a single disease site. The purpose of this study was to demonstrate an efficient method for clinicians to assess the noninferiority o...
BMC medical informatics and decision making
Feb 14, 2019
BACKGROUND: Existing resources to assist the diagnosis of rare diseases are usually curated from the literature that can be limited for clinical use. It often takes substantial effort before the suspicion of a rare disease is even raised to utilize t...
INTRODUCTION: The International Classification of Primary Care, Second version (ICPC-2) aligned with the 10th Revision of the International Classification of Disease (ICD-10) is a standard for primary care epidemiology compendium. ICPC-2 has been als...
OBJECTIVE: Recognizing what physicians know and do not know about a particular disease is one of the keys to designing clinical decision support systems, since these systems can fulfill complementary role by recognizing this boundary. To our knowledg...