AIMC Topic: Knowledge Bases
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EWAS Atlas: a curated knowledgebase of epigenome-wide association studies.
Nucleic acids research
Jan 8, 2019
Epigenome-Wide Association Study (EWAS) has become increasingly significant in identifying the associations between epigenetic variations and different biological traits. In this study, we develop EWAS Atlas (http://bigd.big.ac.cn/ewas), a curated kn...
The Sickle Cell Disease Ontology: enabling universal sickle cell-based knowledge representation.
Database : the journal of biological databases and curation
Jan 1, 2019
Sickle cell disease (SCD) is one of the most common monogenic diseases in humans with multiple phenotypic expressions that can manifest as both acute and chronic complications. Although described more than a century ago, challenges in comprehensive d...
MIRKB: a myocardial infarction risk knowledge base.
Database : the journal of biological databases and curation
Jan 1, 2019
Myocardial infarction (MI) is a common cardiovascular disease and a leading cause of death worldwide. The etiology of MI is complicated and not completely understood. Many risk factors are reported important for the development of MI, including lifes...
Impact of Knowledge-Based Iterative Model Reconstruction on Image Quality and Hemodynamic Parameters in Dynamic Myocardial Computed Tomography Perfusion Using Low-Tube-Voltage Scan: A Feasibility Study.
Journal of computer assisted tomography
Jan 1, 2019
OBJECTIVE: Knowledge-based iterative model reconstruction (IMR) yields diagnostically acceptable image quality in low-dose static computed tomography (CT). We aimed to evaluate the feasibility of IMR in dynamic myocardial computed tomography perfusio...
Aged
Exercise Test
Male
Coronary Artery Disease
Hemodynamics
Feasibility Studies
Contrast Media
Coronary Angiography
Middle Aged
Radiographic Image Interpretation, Computer-Assisted
Computed Tomography Angiography
Cardiac-Gated Imaging Techniques
Algorithms
Iopamidol
Knowledge Bases
Humans
Retrospective Studies
Multidetector Computed Tomography
Female
CDEK: Clinical Drug Experience Knowledgebase.
Database : the journal of biological databases and curation
Jan 1, 2019
The Clinical Drug Experience Knowledgebase (CDEK) is a database and web platform of active pharmaceutical ingredients with evidence of clinical testing as well as the organizations involved in their research and development. CDEK was curated by disam...
Can the Student Outperform the Master? A Plan Comparison Between Pinnacle Auto-Planning and Eclipse knowledge-Based RapidPlan Following a Prostate-Bed Plan Competition.
Technology in cancer research & treatment
Jan 1, 2019
PURPOSE: Pinnacle Auto-Planning and Eclipse RapidPlan are 2 major commercial automated planning engines that are fundamentally different: Auto-Planning mimics real planners in the iterative optimization, while RapidPlan generates static dose objectiv...
An enhanced workflow for variant interpretation in UniProtKB/Swiss-Prot improves consistency and reuse in ClinVar.
Database : the journal of biological databases and curation
Jan 1, 2019
Personalized genomic medicine depends on integrated analyses that combine genetic and phenotypic data from individual patients with reference knowledge of the functional and clinical significance of sequence variants. Sources of this reference knowle...
Design Considerations for a Knowledge Graph: The WATRIMed Use Case.
Studies in health technology and informatics
Jan 1, 2019
The World Health Organization estimates that as much as 80% of the population uses Traditional Medicine (TM) in some form, and in particular, herbal-based Traditional Medicine (HTM). However, TM is mostly orally transmitted and suffers from lack of s...
Automatic Human-like Mining and Constructing Reliable Genetic Association Database with Deep Reinforcement Learning.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Jan 1, 2019
The increasing amount of scientific literature in biological and biomedical science research has created a challenge in continuous and reliable curation of the latest knowledge discovered, and automatic biomedical text-mining has been one of the answ...
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