Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2025
OBJECTIVE: Data extraction from the published literature is the most laborious step in conducting living systematic reviews (LSRs). We aim to build a generalizable, automated data extraction workflow leveraging large language models (LLMs) that mimic...
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2025
OBJECTIVE: The objectives of this study are to synthesize findings from recent research of retrieval-augmented generation (RAG) and large language models (LLMs) in biomedicine and provide clinical development guidelines to improve effectiveness.
BACKGROUND: Adequate patient awareness and understanding of cancer clinical trials is essential for trial recruitment, informed decision making, and protocol adherence. Although large language models (LLMs) have shown promise for patient education, t...
INTRODUCTION: Artificial intelligence (AI) is transforming various aspects of everyday life, including healthcare, through large language models (LLMs) like ChatGPT, Gemini, and Copilot. These systems are increasingly used to disseminate medical info...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2025
OBJECTIVE: To develop an advanced multi-task large language model (LLM) framework for extracting diverse types of information about dietary supplements (DSs) from clinical records.
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2025
OBJECTIVE: This study evaluates the utility of word embeddings, generated by large language models (LLMs), for medical diagnosis by comparing the semantic proximity of symptoms to their eponymic disease embedding ("eponymic condition") and the mean o...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2025
OBJECTIVE: Brief hospital course (BHC) summaries are clinical documents that summarize a patient's hospital stay. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare appl...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2025
OBJECTIVES: Clinical trials (CTs) are essential for improving patient care by evaluating new treatments' safety and efficacy. A key component in CT protocols is the study population defined by the eligibility criteria. This study aims to evaluate the...
MOTIVATION: LLMs like GPT-4, despite their advancements, often produce hallucinations and struggle with integrating external knowledge effectively. While Retrieval-Augmented Generation (RAG) attempts to address this by incorporating external informat...
Background Incomplete clinical histories are a well-known problem in radiology. Previous dedicated quality improvement efforts focusing on reproducible assessments of the completeness of free-text clinical histories have relied on tedious manual anal...
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