AIMC Topic: Leukocytes

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Classification of Human White Blood Cells Using Machine Learning for Stain-Free Imaging Flow Cytometry.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Imaging flow cytometry (IFC) produces up to 12 spectrally distinct, information-rich images of single cells at a throughput of 5,000 cells per second. Yet often, cell populations are still studied using manual gating, a technique that has several dra...

White blood cells detection and classification based on regional convolutional neural networks.

Medical hypotheses
White blood cells (WBC) are important parts of our immune system and they protect our body against infections by eliminating viruses, bacteria, parasites and fungi. There are five types of WBC. These are called Lymphocytes, Monocytes, Eosinophils, Ba...

Automatic recognition of different types of acute leukaemia in peripheral blood by image analysis.

Journal of clinical pathology
AIMS: Morphological differentiation among different blast cell lineages is a difficult task and there is a lack of automated analysers able to recognise these abnormal cells. This study aims to develop a machine learning approach to predict the diagn...

Deep learning approach to peripheral leukocyte recognition.

PloS one
Microscopic examination of peripheral blood plays an important role in the field of diagnosis and control of major diseases. Peripheral leukocyte recognition by manual requires medical technicians to observe blood smears through light microscopy, usi...

Label-Free Identification of White Blood Cells Using Machine Learning.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
White blood cell (WBC) differential counting is an established clinical routine to assess patient immune system status. Fluorescent markers and a flow cytometer are required for the current state-of-the-art method for determining WBC differential cou...

Machine learning algorithms for the detection of spurious white blood cell differentials due to erythrocyte lysis resistance.

Journal of clinical pathology
AIMS: Red blood cell (RBC) lysis resistance interferes with white blood cell (WBC) count and differential; still, its detection relies on the identification of an abnormal scattergram, and this is not clearly adverted by specific flags in the Beckman...

LeukocyteMask: An automated localization and segmentation method for leukocyte in blood smear images using deep neural networks.

Journal of biophotonics
Digital pathology and microscope image analysis is widely used in comprehensive studies of cell morphology. Identification and analysis of leukocytes in blood smear images, acquired from bright field microscope, are vital for diagnosing many diseases...

Feature extraction using traditional image processing and convolutional neural network methods to classify white blood cells: a study.

Australasian physical & engineering sciences in medicine
White blood cells play a vital role in monitoring health condition of a person. Change in count and/or appearance of these cells indicate hematological disorders. Manual microscopic evaluation of white blood cells is the gold standard method, but the...

More Than Just a Removal Service: Scavenger Receptors in Leukocyte Trafficking.

Frontiers in immunology
Scavenger receptors are a highly diverse superfamily of proteins which are grouped by their inherent ability to bind and internalize a wide array of structurally diverse ligands which can be either endogenous or exogenous in nature. Consequently, sca...

Fine-grained leukocyte classification with deep residual learning for microscopic images.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Leukocyte classification and cytometry have wide applications in medical domain, previous researches usually exploit machine learning techniques to classify leukocytes automatically. However, constrained by the past developm...