AIMC Topic: Limit of Detection

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Machine Learning-Enhanced Chemiresistive Sensors for Ultra-Sensitive Detection of Methanol Adulteration in Alcoholic Beverages.

ACS sensors
Methanol poisoning poses significant health risks, particularly in less developed countries, where adulterated alcoholic beverages often lead to severe morbidity and mortality. Current diagnostic methods, such as gas-liquid chromatography and blood g...

A miniaturized liver function detection system with machine learning enhancing strategy.

Biosensors & bioelectronics
Serum alanine aminotransferase (ALT) is one of the most sensitive indicators of liver function and is crucial in diagnosing acute liver injury (ALI). However, its widespread clinical application is limited due to expensive equipment, detection delays...

Machine learning-driven 3D-QSAR models facilitated rapid on-site broad-spectrum immunoassay of (fluoro)quinolones using evanescent wave fiber-embedded optofluidic biochip.

Biosensors & bioelectronics
(Fluoro)quinolones (FQs) pose significant threats to public health due to their widespread use and persistence in food and water sources. Given the extensive variety of FQs, testing each compound individually is prohibitively expensive and time-consu...

Single-Protein Determinations by Magnetofluorescent Qubit Imaging with Artificial-Intelligence Augmentation at the Point-Of-Care.

ACS nano
Conventional point-of-care testing (POCT) has limitations in sensitivity with high risks of missed detection or false positive, which restrains its applications for routine outpatient care analysis and early clinical diagnosis. By merits of the cutti...

Tyramide signal amplification for a highly sensitive multiplex immunoassay based on encoded hydrogel microparticles.

The Analyst
Proteins play a crucial role as mediators of immune regulation, homeostasis, and metabolism, making their quantification essential for understanding disease mechanisms in biomedical research and clinical diagnostics. However, conventional methods whe...

Histidine-engineered Cu-BTC nanozyme with enhanced laccase-like activity combining the machine learning for precise recognition of Beta-lactam antibiotics.

Biosensors & bioelectronics
Although nanozyme sensor arrays can simultaneously recognize multiple target substances, they are currently rarely used for identifying Beta-lactam antibiotics (BLs). This may be due to the lower catalytic performance of some nanozymes in practical a...

Simultaneous determination of pesticide residues and rapid discrimination of corn production origin using ambient ionization mass spectrometry combined with machine learning.

Food chemistry
Food traceability is a critical aspect of quality control and food safety. In this study, a high-throughput analysis system with an analysis time of 13 min was developed for the detection of pesticide residues in corn, achieving low limits of detecti...

Detection of ninhydrin-glyphosate in groundwater via the colour chart-assisted digital camera method.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
This study introduces a novel application of a one-time and multistandard colour chart across three instruments using colour visible spectrophotometer (colour VS), digital single-lens reflex (DSLR) cameras, and mobile camera (MC) analysis to quantify...

Aptamer-functionalized graphene quantum dots combined with artificial intelligence detect bacteria for urinary tract infections.

Frontiers in cellular and infection microbiology
OBJECTIVES: Urinary tract infection is one of the most prevalent forms of bacterial infection, and prompt and efficient identification of pathogenic bacteria plays a pivotal role in the management of urinary tract infections. In this study, we propos...

A fluorescence probe-smartphone-machine learning integrated platform for the visual and intelligent detection of imidacloprid in agricultural products.

Food chemistry
Imidacloprid is a pesticide commonly used in agriculture production. Portable and accurate detection of imidacloprid residues is of great significance to food safety and human health. Herein, a red-emitting rare earth complex (Eu-IMDC) probe is prepa...