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Liver Neoplasms

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Novel deep learning-based solution for identification of prognostic subgroups in liver cancer (Hepatocellular carcinoma).

BMC bioinformatics
BACKGROUND: Liver cancer (Hepatocellular carcinoma; HCC) prevalence is increasing and with poor clinical outcome expected it means greater understanding of HCC aetiology is urgently required. This study explored a deep learning solution to detect bio...

A study of generalization and compatibility performance of 3D U-Net segmentation on multiple heterogeneous liver CT datasets.

BMC medical imaging
BACKGROUND: Most existing algorithms have been focused on the segmentation from several public Liver CT datasets scanned regularly (no pneumoperitoneum and horizontal supine position). This study primarily segmented datasets with unconventional liver...

A Single Institution's Experience With Robotic Minor and Major Hepatectomy.

The American surgeon
BACKGROUND: Minimally invasive liver resection is gradually becoming the preferred technique to treat liver tumors due its salutary benefits when compared with traditional "open" method. While robotic technology improves surgeon dexterity to better p...

Deep learning radiomics based on contrast enhanced computed tomography predicts microvascular invasion and survival outcome in early stage hepatocellular carcinoma.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
OBJECTIVE: To evaluate the performance of a deep learning (DL)-based radiomics strategy on contrast-enhanced computed tomography (CT) to predict microvascular invasion (MVI) status and clinical outcomes, recurrence-free survival (RFS) and overall sur...

Automatic liver tumor localization using deep learning-based liver boundary motion estimation and biomechanical modeling (DL-Bio).

Medical physics
PURPOSE: Recently, two-dimensional-to-three-dimensional (2D-3D) deformable registration has been applied to deform liver tumor contours from prior reference images onto estimated cone-beam computed tomography (CBCT) target images to automate on-board...

Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization.

Cell reports. Medicine
Although transarterial chemoembolization (TACE) is the most widely used treatment for intermediate-stage, unresectable hepatocellular carcinoma (HCC), it is only effective in a subset of patients. In this study, we combine clinical, radiological, and...

A deep-learning-based prediction model for the biodistribution of Y microspheres in liver radioembolization.

Medical physics
BACKGROUND: Radioembolization with Y microspheres is a treatment approach for liver cancer. Currently, employed dosimetric calculations exhibit low accuracy, lacking consideration of individual patient, and tissue characteristics.

Predicting microvascular invasion in hepatocellular carcinoma: a deep learning model validated across hospitals.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: The accuracy of estimating microvascular invasion (MVI) preoperatively in hepatocellular carcinoma (HCC) by clinical observers is low. Most recent studies constructed MVI predictive models utilizing radiological and/or radiomics features ...

A Liver Segmentation Method Based on the Fusion of VNet and WGAN.

Computational and mathematical methods in medicine
Accurate segmentation of liver images is an essential step in liver disease diagnosis, treatment planning, and prognosis. In recent years, although liver segmentation methods based on 2D convolutional neural networks have achieved good results, there...

Multi-Source Transfer Learning Via Multi-Kernel Support Vector Machine Plus for B-Mode Ultrasound-Based Computer-Aided Diagnosis of Liver Cancers.

IEEE journal of biomedical and health informatics
B-mode ultrasound (BUS) imaging is a routine tool for diagnosis of liver cancers, while contrast-enhanced ultrasound (CEUS) provides additional information to BUS on the local tissue vascularization and perfusion to promote diagnostic accuracy. In th...