BACKGROUND: Given the accelerated aging population in China, the number of disabled elderly individuals is increasing, and depression is a common mental disorder among older adults. This study aims to establish an effective model for predicting depre...
BACKGROUND: Early diagnosis and accurate prognosis of cognitive decline in Alzheimer's disease (AD) is important to timely assignment to optimal treatment modes. We aimed to develop a deep learning model to predict cognitive conversion to guide re-as...
BACKGROUND: Due to the ageing population and evolving lifestyles occurring in China, middle-aged and elderly populations have become high-risk groups for cardiovascular disease (CVD). The aim of this study was to analyse the incidence characteristics...
The journal of prevention of Alzheimer's disease
Feb 6, 2025
BACKGROUND: Mild cognitive impairment (MCI) and preclinical MCI (e.g., subjective cognitive decline, SCD) are considered risk states of dementia, such as Alzheimer's Disease (AD). However, it is challenging to accurately predict conversion from norma...
INTRODUCTION: Speech impediments (SIs) are increasingly prevalent among middle-aged and older adults, raising concerns within public health. Early detection of potential SI in this demographic is critical. This study investigates the potential of Act...
OBJECTIVES: Knee subchondral bone marrow lesions (BMLs) are one of the hallmark features of structural osteoarthritis (OA) and are potential targets for statins' disease-modifying effect. We aimed to determine the association between statin use and l...
Risk of U.S. Army soldier suicide-related behaviors increases substantially after separation from service. As universal prevention programs have been unable to resolve this problem, a previously reported machine learning model was developed using pre...
BACKGROUND: Early detection and diagnosis of cancer are vital to improving outcomes for patients. Artificial intelligence (AI) models have shown promise in the early detection and diagnosis of cancer, but there is limited evidence on methods that ful...
Molecular genetics and genomics : MGG
Jan 24, 2025
Stroke is a leading cause of death and disability globally, particularly in China. Identifying risk factors for stroke at an early stage is critical to improving patient outcomes and reducing the overall disease burden. However, the complexity of str...
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