Neurodegenerative diseases are devastating conditions characterized by progressive cognitive decline with few available treatments. Neurodegeneration can be quantified in vertebrate and invertebrate models of disease by analysis of vacuolation - the ...
Journal of chemical information and modeling
Sep 24, 2025
Molecular property prediction is of great significance in drug design and materials science. However, due to the complexity and diversity of molecular structures, existing methods often struggle to simultaneously capture both the local chemical envir...
Sleep problems among young adults pose a major public health challenge. Leveraging nationwide health surveys and registers from Denmark, we investigated patterns of sleep problems from late adolescence to adulthood and explored early life-course dete...
BACKGROUND: Immunogenic cell death (ICD) triggers antitumor immune responses and plays a critical role in shaping the tumor microenvironment (TME). However, its specific contribution to lung adenocarcinoma (LUAD) progression and immunotherapy respons...
Scandinavian journal of trauma, resuscitation and emergency medicine
Sep 24, 2025
BACKGROUND: Accurately predicting mortality in patients with skin and soft-tissue infections (SSTIs) remains challenging. Machine learning models offer rapid processing, algorithmic impartiality, and strong predictive accuracy, which may improve earl...
BACKGROUND AND OBJECTIVES: Wilson disease (WD), an inherited copper metabolism disorder, is a cause of acute-on-chronic liver failure (ACLF), posing life-threatening risks due to rapid progression. This study aimed to develop a machine learning (ML)-...
BACKGROUND: Infertility affects approximately 15% of couples globally, with assisted reproductive technologies (ARTs) becoming the primary interventions. Despite the growing use of ARTs, success rates have plateaued at around 30%, highlighting the ne...
BACKGROUND: The prevalence of depression symptoms, the third most disabling disease worldwide, is as high as 11.5%-21.1% in China's middle-aged and elderly population and increases significantly with age. It is crucial to identify high-risk groups ef...
BACKGROUND: Drought is a global challenge that severely restricts crop yields and threatens food security. Plants respond to drought stress by modulating gene expression before visible phenotypic changes occur. However, most studies of drought resist...
BACKGROUND: Asthma is a chronic inflammatory disorder that adversely affects the quality of life, particularly in older adults. The coexistence of depression in asthma patients complicates their management and exacerbates health outcomes. This study ...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.