In an nanotoxicity system, cell-nanoparticle (NP) interaction leads to the surface adsorption, uptake, and changes into nuclei/cell phenotype and chemistry, as an indicator of oxidative stress, genotoxicity, and carcinogenicity. Different types of n...
Best practice & research. Clinical gastroenterology
Dec 29, 2020
Artificial intelligence (AI) research in endoscopy is being translated at rapid pace with a number of approved devices now available for use in luminal endoscopy. However, the published literature for AI in biliopancreatic endoscopy is predominantly ...
The acquisition of large-scale medical image data, necessary for training machine learning algorithms, is hampered by associated expert-driven annotation costs. Mining hospital archives can address this problem, but labels often incomplete or noisy, ...
Journal of integrative bioinformatics
Dec 29, 2020
G protein-coupled receptors (GPCRs) play an essential role in critical human activities, and they are considered targets for a wide range of drugs. Accordingly, based on these crucial roles, GPCRs are mainly considered and focused on pharmaceutical r...
Journal of integrative bioinformatics
Dec 29, 2020
Breast cancer is the leading diseases of death in women. It induces by a genetic mutation in breast cancer cells. Genetic testing has become popular to detect the mutation in genes but test cost is relatively expensive for several patients in develop...
BACKGROUND: Entity normalization is an important information extraction task which has gained renewed attention in the last decade, particularly in the biomedical and life science domains. In these domains, and more generally in all specialized domai...
Systematic perturbation of cells followed by comprehensive measurements of molecular and phenotypic responses provides informative data resources for constructing computational models of cell biology. Models that generalize well beyond training data ...
Allosteric molecules provide a powerful means to modulate protein function. However, the effect of such ligands on distal orthosteric sites cannot be easily described by classical docking methods. Here, we applied machine learning (ML) approaches to ...
International journal of environmental research and public health
Dec 28, 2020
According to the World Health Organization, about 20 million people are infected with Hepatitis E every year. In 2015, there were 44,000 deaths due to HEV infection worldwide. Food, water and climate are key factors that affect the outbreak of Hepati...
International journal of environmental research and public health
Dec 28, 2020
Evidence from some studies suggest that osteoarthritis (OA) patients are often prescribed non-steroidal anti-inflammatory drugs (NSAIDs) that are not in accordance with their cardiovascular (CV) or gastrointestinal (GI) risk profiles. However, no suc...
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