European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Jun 17, 2025
Nearly 60 % of individuals with bipolar disorder (BD) are initially classified as major depressive disorder (MDD) patients, resulting in inappropriate drug treatment. Identifying reliable biomarkers for the differential diagnosis between MDD and BD p...
BACKGROUND: Thyroid diseases are the second most common hormonal disorders, necessitating accurate diagnostics. Advances in artificial intelligence and radiomics have enhanced diagnostic precision by analyzing quantitative imaging features. However, ...
Journal of chemical information and modeling
Jun 17, 2025
Accurate prediction of drug-protein interactions is crucial for drug discovery. Due to the bottleneck of traditional scoring functions, many machine learning scoring functions (MLSFs) have been proposed for structure-based drug screening. However, ex...
Journal of chemical information and modeling
Jun 17, 2025
We demonstrate the usefulness of general atom- and bond-level density functional theory (DFT) descriptors to enhance the performance of neural networks for general reaction condition prediction. We treat condition prediction as a multiclass classific...
OBJECTIVES: Unplanned pneumonia readmissions increase patient morbidity, mortality and healthcare costs. Among pneumonia patients, the middle-aged and elderly (≥45 years old) have a significantly higher risk of readmission compared with the young. Gi...
Journal of cancer research and clinical oncology
Jun 17, 2025
BACKGROUND: With the improvement of imaging, the screening rate of Pulmonary nodules (PNs) has further increased, but their identification of High-Risk Prognostic Pathological Components (HRPPC) is still a major challenge. In this study, we aimed to ...
Emerging infectious diseases demand comprehensive containment strategies, encompassing early detection and patient monitoring. Conventional diagnostic tests often suffer from low sensitivity, reliance on specialized equipment, and binary (positive/ne...
BACKGROUND: Numerous studies have revealed abnormalities in EEG microstate in insomnia, primarily quantified using linear features, whereas nonlinear metrics remain underexplored. This study aimed to compare linear and nonlinear features and further ...
Computer methods and programs in biomedicine
Jun 16, 2025
BACKGROUND AND OBJECTIVE: General practice (GP) pre-diagnosis, a key task in disease triage, directs patients to suitable departments despite limited data and multi-label classification challenges. To address this issue, a framework with dimensionali...
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