Acute kidney injury is a common and critical complication in patients with community-acquired pneumonia who are admitted to intensive care units, substantially increasing their risk of short-term mortality. To enhance early clinical decision-making, ...
Similarity lies at the core of theories of memory and perception. To understand similarity relations among complex items like text and images, researchers often rely on machine learning to derive high-dimensional vector representations of those items...
BACKGROUND: While machine learning (ML) technologies have shifted from development to real-world deployment over the past decade, US health care providers and hospital administrators have increasingly embraced ML, particularly through its integration...
BACKGROUND: Renal cell carcinoma (RCC), which accounts for 70-90% of kidney malignancies, remains difficult to diagnose early due to its asymptomatic onset and the lack of reliable biomarkers. This study aimed to develop a robust diagnostic model by ...
Timely and precise therapeutic drug monitoring (TDM) is critical for managing pharmacokinetic variability and optimizing individualized therapy, particularly during public health crises such as the COVID-19 pandemic. Herein, we optimized integrated m...
BACKGROUND: Malocclusion is a common anomaly and is frequently observed in children and adults. Early detection and treatment of malocclusion is necessary to prevent and minimize complications. Therefore, developing a tool to check dentition at an ea...
BACKGROUND AND OBJECTIVES: Women's empowerment is a vital issue in lower-middle-income developing countries like Bangladesh, where it plays a pivotal role in advancing development across the nation. Thus, this study aimed to identify the influential ...
International journal of pharmaceutics
Dec 8, 2025
Driven by the Food and Drug Administration's Quality-by-Design initiative and the advancements of Industry 4.0, the pharmaceutical industry is transitioning from traditional batch manufacturing to advanced manufacturing. This transition requires resh...
Journal of chemical information and modeling
Dec 8, 2025
MiRNA serves as a key noncoding RNA regulating gene expression and is frequently targeted as a therapeutic small molecule (SM). However, relying solely on the experimental identification of SM-miRNA interactions proves costly and inefficient. To addr...
Journal of chemical information and modeling
Dec 8, 2025
The drug discovery process is inherently lengthy, complex, and costly, with high attrition rates driven by safety concerns, limited efficacy, and regulatory barriers. AI-driven computational methods have become crucial in accelerating this process by...
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