The void spot assay has gained popularity as a way of assessing functional bladder voiding parameters in mice, but analyzing the size and distribution of urine spot patterns on filter paper with software remains problematic due to inter-laboratory di...
Journal of clinical hypertension (Greenwich, Conn.)
Mar 1, 2025
Carotid-femoral pulse wave velocity (cf-PWV) is an important but difficult to obtain measure of arterial stiffness and an independent predictor of cardiovascular events and all-cause mortality. The objective of this study was to develop a predictive ...
International journal for numerical methods in biomedical engineering
Mar 1, 2025
The complex mechanical environment of peripheral arteries makes stents with poor torsional performance more prone to fracture, and stent fracture is considered a precursor to in-stent restenosis (ISR). Therefore, studying the torsional performance of...
A successful drug needs to combine several properties including high potency and good pharmacokinetic (PK) properties to sustain efficacious plasma concentration over time. To estimate required doses for preclinical animal efficacy models or for the ...
Pain is a complex, multidimensional experience involving significant challenges in both diagnosis and management. While acute pain serves as a critical warning mechanism, chronic pain encompasses intricate biological, psychological, and social compon...
BACKGROUND: Gastric cancer (GC) is considered a highly heterogeneous disease, and currently, a comprehensive approach encompassing molecular data from various biological levels is lacking.
The Journal of the Acoustical Society of America
Mar 1, 2025
Vocal intensity is quantified by sound pressure level (SPL). The SPL can be measured by either using a sound level meter or by comparing the energy of the recorded speech signal with the energy of the recorded calibration tone of a known SPL. Neither...
The bacterial cell wall is crucial for maintaining the integrity of bacterial cells. UDP-N-acetylglucosamine 1-carboxyethylene transferase (MurA) is an important enzyme involved in bacterial cell wall synthesis. Therefore, it is an important target f...
Within a recent decade, graph neural network (GNN) has emerged as a powerful neural architecture for various graph-structured data modelling and task-driven representation learning problems. Recent studies have highlighted the remarkable capabilities...
The beam walk is widely used to study coordination and balance in rodents. While the task has ethological validity, the main endpoints of "foot slip counts" and "time to cross" are prone to human-rater variability and offer limited sensitivity and sp...
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