Clinical definitions of asthma fail to capture the heterogeneity of immune dysfunction in severe, treatment-refractory disease. Applying mass cytometry and machine learning to bronchoalveolar lavage (BAL) cells, we find that corticosteroid-resistant ...
Proceedings of the National Academy of Sciences of the United States of America
Apr 13, 2021
Intracellular phase separation of proteins into biomolecular condensates is increasingly recognized as a process with a key role in cellular compartmentalization and regulation. Different hypotheses about the parameters that determine the tendency of...
Proceedings of the National Academy of Sciences of the United States of America
Apr 6, 2021
Subclasses of lymphocytes carry different functional roles to work together and produce an immune response and lasting immunity. Additionally to these functional roles, T and B cell lymphocytes rely on the diversity of their receptor chains to recogn...
OBJECTIVE: The Fugl-Meyer motor scale (FM) is a well-validated measure for assessing upper extremity and lower extremity motor functions in people with stroke. The FM contains numerous items (50), which reduces its clinical usability. The purpose of ...
The Journal of the Acoustical Society of America
Apr 1, 2021
This study proposes a sound classification model for natural disasters. Deep learning techniques, a convolutional neural network (CNN) and long short-term memory (LSTM), were used to train two individual classifiers. The study was conducted using a d...
The usage of artificial intelligence to evaluate histological images was recently explored in many different areas of pathology. Studies focusing on nephropathology demonstrated that algorithms could be trained to identify various structures of the k...
Journal of gastroenterology and hepatology
Apr 1, 2021
Gut microbiota has been shown to associate with the development of gastrointestinal diseases. In the last decade, development in whole metagenome sequencing and 16S rRNA sequencing technology has dramatically accelerated the gut microbiome's research...
Journal of gastroenterology and hepatology
Apr 1, 2021
The maturing development in artificial intelligence (AI) and genomics has propelled the advances in intestinal diseases including intestinal cancer, inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). On the other hand, colorectal c...
Journal of gastroenterology and hepatology
Apr 1, 2021
Gastrointestinal cancer maintains the highest incidence and mortality rate among all cancers globally. In addition to genetic causes, it has been reported that individuals' diet and composition of the gastrointestinal microbiome have profound impacts...
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