It is well known that machine learning models require a high amount of annotated data to obtain optimal performance. Labelling Computed Tomography (CT) data can be a particularly challenging task due to its volumetric nature and often missing and/or ...
Metabolic dysfunction-associated fatty liver disease (MAFLD), a global epidemic affecting 25% of adults, is driven by immune-metabolic dysregulation, yet the causal mechanisms linking immune cell-specific gene perturbations to disease progression rem...
Early accurate drug prediction is crucial in clinical decision support, where privacy of the patient data is a paramount importance. In this study, we introduce a fused weighted adaptive federated learning (FWAFL) framework to achieve joint training ...
The destructive impacts of wildfires on people, property and the environment have dramatically increased, especially in the Wildland-Urban Interface (WUI) in California. In these areas structures are threatened by both approaching flames and lofted e...
Clinical trials demonstrate that screening can reduce lung cancer mortality by over 20%. However, lung cancer screening effectiveness (reduction in lung cancer specific mortality) may vary by personal risk-factors. Here we evaluate heterogeneity in l...
Accurate variant penetrance estimation is crucial for precision medicine. We constructed machine learning (ML) models for 10 diseases using 1,347,298 participants with electronic health records, then applied them to an independent cohort with linked ...
To assess strategies for enhancing the generalizability of healthcare artificial intelligence models, we analyzed the impact of preprocessing approaches applied to medical free text, compared single- versus multiple-institution data models, and evalu...
BACKGROUND: Untreated dental caries is the most common health condition worldwide. Therefore, new strategies need to be developed to reduce the manifestations of dental caries.
3D printing has brought significant changes to manufacturing sectors, making it possible to produce intricate, multi-layered designs with greater ease. This study focuses on optimizing the compressive strength (CS) of functionally graded multi-materi...
Despite the significance of enhancing the quality of life (QoL) and overall health status (including physical, mental, social, and spiritual well-being) among individuals who have survived cancer, the existing prediction model for QoL and health stat...
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