Cerebral small vessel disease (CSVD) is a global brain disorder that is characterized by a series of clinical, neuroimaging, and neuropathological manifestations. However, the molecular pathophysiological mechanisms of CSVD have not been thoroughly i...
European journal of nuclear medicine and molecular imaging
Feb 11, 2025
PURPOSE: This study aims to develop and validate a deep learning framework designed to eliminate the second CT scan of dual-tracer total-body PET/CT imaging.
Clinical oncology (Royal College of Radiologists (Great Britain))
Feb 11, 2025
AIMS: Medulloblastoma (MB) is the most prevalent malignant brain tumour in children, characterised by substantial molecular heterogeneity across its subgroups. Accurate classification is pivotal for personalised treatment strategies and prognostic as...
International journal of biological macromolecules
Feb 11, 2025
The purpose of this study was to investigate the molecular structure of NRG-1 protein and its mechanism of action in adult hypertensive heart failure. The amino acid sequence of NRG-1 protein was analyzed by bioinformatics method. High-throughput seq...
Clinical pharmacology and therapeutics
Feb 11, 2025
The current standard method for the analysis of potential drug-drug interactions (pDDIs) is time-consuming and includes the use of multiple clinical decision support systems (CDSSs) and the interpretation by healthcare professionals. With the emergen...
BACKGROUND AND OBJECTIVE: Autoimmune encephalitis (AE) is an immune-mediated disease. Some patients experience persistent cognitive deficits despite receiving immunotherapy. We aimed to develop a prediction model for long-term cognitive outcomes in p...
INTRODUCTION: Over one-third of the population in the United States (US) has prediabetes. Unfortunately, underserved population in the United States face a higher burden of prediabetes compared to urban areas, increasing the risk of stroke and heart ...
Alzheimer's disease (AD) is a degenerative neurological condition characterized by a progressive decline in cognitive abilities, resulting in memory impairment and limitations in performing daily tasks. Timely and precise identification of AD holds p...
American journal of veterinary research
Feb 11, 2025
OBJECTIVE: To capture veterinary professionals' perspectives and applications of AI in veterinary care. This study assesses the perceived benefits, challenges, and potential areas where AI could enhance veterinary medicine and practice workflows.
Proceedings of the National Academy of Sciences of the United States of America
Feb 11, 2025
In wearable smart systems, continuous monitoring and accurate classification of different sleep-related conditions are critical for enhancing sleep quality and preventing sleep-related chronic conditions. However, the requirements for device-skin cou...
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