AIMC Topic: Margins of Excision
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Reframing robotics in Mohs surgery for rare cutaneous sarcomas: conceptual promise and clinical realities in precision oncology.
Journal of robotic surgery
Aug 9, 2025
Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive cutaneous sarcoma in which achieving histologically negative margins is paramount to minimizing recurrence. Mohs micrographic surgery (MMS) has transformed margin control in DFSP by...
Artificial intelligence for early gastric cancer boundary recognition in NBI and nF-NBI endoscopic images.
Scandinavian journal of gastroenterology
Jun 2, 2025
OBJECTIVES: Precise delineation of early gastric cancer (EGC) margins is essential for complete resection during endoscopic submucosal dissection. This study aimed to develop deep learning-based models for EGC boundary detection in narrow-band imagin...
FACT: foundation model for assessing cancer tissue margins with mass spectrometry.
International journal of computer assisted radiology and surgery
Apr 4, 2025
PURPOSE: Accurately classifying tissue margins during cancer surgeries is crucial for ensuring complete tumor removal. Rapid Evaporative Ionization Mass Spectrometry (REIMS), a tool for real-time intraoperative margin assessment, generates spectra th...
Multiparametric MRI and transfer learning for predicting positive margins in breast-conserving surgery: a multi-center study.
International journal of surgery (London, England)
Apr 1, 2025
This study aimed to predict positive surgical margins in breast-conserving surgery (BCS) using multiparametric MRI (mpMRI) and radiomics. A retrospective analysis was conducted on data from 444 BCS patients from three Chinese hospitals between 2019 a...
Raman spectroscopy for colorectal tumor margin assessment: A promising tool for real-time surgical delimitation.
Talanta
Feb 21, 2025
Raman spectroscopy is a promising non-invasive technique not only for the rapid and accurate detection of colorectal cancer (CRC) but also for the identification of positive surgical margins. In this study, micro-Raman spectroscopy was used to explor...
Enhancing surgical precision in squamous cell carcinoma of the head and neck: Hyperspectral imaging and artificial intelligence for improved margin assessment in an ex vivo setting.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jan 30, 2025
BACKGROUND: Head and neck cancers, constituting 3-5% of all cancer cases, often require surgical resection for optimal outcomes. Achieving complete resection (R0) is crucial, but current methods, relying on white light endoscopy and microscopy, have ...
Untargeted Swab Touch Spray-Mass Spectrometry Analysis with Machine Learning for On-Site Breast Surgical Margin Assessment.
Analytical chemistry
Jan 19, 2025
Direct sampling mass spectrometry (MS) has rapidly advanced with the development of ambient ionization MS techniques. Swab touch-spray (TS)-MS has shown promise for rapid clinical diagnostics. However, commercially available swabs are notorious for t...
Stimulated Raman Histology and Artificial Intelligence Provide Near Real-Time Interpretation of Radical Prostatectomy Surgical Margins.
The Journal of urology
Dec 17, 2024
PURPOSE: Balancing surgical margins and functional outcomes is crucial during radical prostatectomy for prostate cancer. Stimulated Raman histology (SRH) is a novel, real-time imaging technique that provides histologic images of fresh, unprocessed, a...
A systematic scoping review exploring variation in practice in specimen mammography for Intraoperative Margin Analysis in Breast Conserving Surgery and the role of artificial intelligence in optimising diagnostic accuracy.
European journal of radiology
Oct 9, 2024
PURPOSE: Specimen Mammography (SM) is commonly used in Breast Conserving Surgery (BCS) for intraoperative margin analysis. A systematic scoping review was conducted to identify sources of methodological variation in Specimen Mammography Interpretatio...
Deep learning-enabled fluorescence imaging for surgical guidance: training for oral cancer depth quantification.
Journal of biomedical optics
Sep 18, 2024
SIGNIFICANCE: Oral cancer surgery requires accurate margin delineation to balance complete resection with post-operative functionality. Current fluorescence imaging systems provide two-dimensional margin assessment yet fail to quantify tumor depth p...
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