AIMC Topic: MCF-7 Cells

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Exploring photoacoustic spectroscopy-based machine learning together with metabolomics to assess breast tumor progression in a xenograft model ex vivo.

Laboratory investigation; a journal of technical methods and pathology
In the current study, a breast tumor xenograft was established in athymic nude mice by subcutaneous injection of the MCF-7 cell line and assessed the tumor progression by photoacoustic spectroscopy combined with machine learning tools. The advancemen...

Analyzing protein dynamics from fluorescence intensity traces using unsupervised deep learning network.

Communications biology
We propose an unsupervised deep learning network to analyze the dynamics of membrane proteins from the fluorescence intensity traces. This system was trained in an unsupervised manner with the raw experimental time traces and synthesized ones, so nei...

A new diarylhexane and two new diarylpropanols from the roots of .

Natural product research
A new diarylhexane, kneglobularone B () and two new diarylpropanols, kneglobularols A - B () along with seven known compounds () were isolated and characterized from the roots of It is the first time to find arylpropyl quinone () and isoflavone () i...

Photoelectrochemical detection of circulating tumor cells based on aptamer conjugated CuO as signal probe.

Biosensors & bioelectronics
In this work, a sensitive and reliable photoelectrochemical (PEC) biosensor was proposed based on hexagonal carbon nitride tubes (HCNT) as photoactive material for detection of circulating tumor cells (CTCs). Magnetic FeO nanospheres (MNs) and CuO na...

System-level responses to cisplatin in pro-apoptotic stages of breast cancer MCF-7 cell line.

Computational biology and chemistry
Cisplatin ceases cell division and induces apoptosis in cancer cell lines. It is well established that cisplatin alters the expression of many genes involved in several cellular processes and pathways including transcription, p53 signaling pathway, a...

Phytochemical analysis and evaluation of the antioxidant and antiproliferative effects of Tucumã oil nanocapsules in breast adenocarcinoma cells (MCF-7).

Natural product research
In this work was to develop an inedited nanocapsule with tucumã oil (). The oil presents of phytosterols (squalene and β-sitosterol), --beta-carotene, acids oleic and palmitic. Antioxidant activity showed a good performance in DPPH and ABTS assays. T...

The optoelectronic microrobot: A versatile toolbox for micromanipulation.

Proceedings of the National Academy of Sciences of the United States of America
Microrobotics extends the reach of human-controlled machines to submillimeter dimensions. We introduce a microrobot that relies on optoelectronic tweezers (OET) that is straightforward to manufacture, can take nearly any desirable shape or form, and ...

An Intelligent DNA Nanorobot with Enhanced Protein Lysosomal Degradation of HER2.

Nano letters
DNA nanorobots have emerged as new tools for nanomedicine with the potential to ameliorate the delivery and anticancer efficacy of various drugs. DNA nanostructures have been considered one of the most promising nanocarriers. In the present study, we...

Equivalent circuit models for a biomembrane impedance sensor and analysis of electrochemical impedance spectra based on support vector regression.

Medical & biological engineering & computing
In this study, an electrochemical impedance biosensor was developed as a simple and fast method for real-time monitoring of biofilm binding properties via continuous impedance spectroscopy. To prepare the sensing membrane, cells were immobilized onto...

Convolutional neural network for cell classification using microscope images of intracellular actin networks.

PloS one
Automated cell classification is an important yet a challenging computer vision task with significant benefits to biomedicine. In recent years, there have been several studies attempted to build an artificial intelligence-based cell classifier using ...