AIMC Topic: MCF-7 Cells
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Equivalent circuit models for a biomembrane impedance sensor and analysis of electrochemical impedance spectra based on support vector regression.
Medical & biological engineering & computing
Apr 2, 2019
In this study, an electrochemical impedance biosensor was developed as a simple and fast method for real-time monitoring of biofilm binding properties via continuous impedance spectroscopy. To prepare the sensing membrane, cells were immobilized onto...
Convolutional neural network for cell classification using microscope images of intracellular actin networks.
PloS one
Mar 13, 2019
Automated cell classification is an important yet a challenging computer vision task with significant benefits to biomedicine. In recent years, there have been several studies attempted to build an artificial intelligence-based cell classifier using ...
Humans
Female
Reproducibility of Results
Breast Neoplasms
Cell Line, Tumor
Neural Networks, Computer
Machine Learning
Algorithms
Pattern Recognition, Automated
Actins
Cytoplasm
Cytoskeleton
Breast
Image Processing, Computer-Assisted
Automation
MCF-7 Cells
Cell Line
Models, Statistical
Microscopy, Fluorescence
Transfer Learning with Deep Convolutional Neural Networks for Classifying Cellular Morphological Changes.
SLAS discovery : advancing life sciences R & D
Jan 14, 2019
The quantification and identification of cellular phenotypes from high-content microscopy images has proven to be very useful for understanding biological activity in response to different drug treatments. The traditional approach has been to use cla...
Multifunctional luminescent immuno-magnetic nanoparticles: toward fast, efficient, cell-friendly capture and recovery of circulating tumor cells.
Journal of materials chemistry. B
Dec 19, 2018
Highly efficient isolation and recovery of viable circulating tumor cells (CTCs) from the blood of patients is an important precondition to address the current dilemma of insufficient CTC studies, and can promote the development of individualized ant...
Designing Anticancer Peptides by Constructive Machine Learning.
ChemMedChem
May 29, 2018
Constructive (generative) machine learning enables the automated generation of novel chemical structures without the need for explicit molecular design rules. This study presents the experimental application of such a deep machine learning model to d...
Autonomous Magnetic Microrobots by Navigating Gates for Multiple Biomolecules Delivery.
Small (Weinheim an der Bergstrasse, Germany)
May 8, 2018
The precise delivery of biofunctionalized matters is of great interest from the fundamental and applied viewpoints. In spite of significant progress achieved during the last decade, a parallel and automated isolation and manipulation of rare analyte,...
Chromosome-wide gene dosage rebalance may benefit tumor progression.
Molecular genetics and genomics : MGG
Mar 15, 2018
The high-risk of tumor initiation in patients with Turner syndrome (TS) characterized by X chromosome monosomy in women has been well established and aneuploidy, defined as an abnormal number of chromosomes, is a common feature in human cancer. Howev...
Cytotoxic activity of the bioactive principles from Ficus burtt-davyi.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
Dec 26, 2017
Ficus burtt-davyi (Moraceae) is a medicinal plant species indigenous to Southern Africa. In this study, a phytochemical and cytotoxic investigation on F. burtt-davyi was conducted to evaluate its ethno-medicinal use. The phytochemical study of the fr...
Selective cytotoxic and genotoxic activities of 5-(2-bromo-5-methoxybenzylidene)-thiazolidine-2,4-dione against NCI-H292 human lung carcinoma cells.
Pharmacological reports : PR
Nov 22, 2017
BACKGROUND: Thiazolidine-2,4-dione ring system is used as a pharmacophore to build various heterocyclic compounds aimed to interact with biological targets. In the present study, benzylidene-2,4-thiazolidinedione derivatives (compounds 2-5) were synt...
Integrating DNA structure switch with branched hairpins for the detection of uracil-DNA glycosylase activity and inhibitor screening.
Talanta
Nov 22, 2017
The detection of uracil-DNA glycosylase (UDG) activity is pivotal for its biochemical studies and the development of drugs for UDG-related diseases. Here, we explored an integrated DNA structure switch for high sensitive detection of UDG activity. Th...
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