Advanced materials (Deerfield Beach, Fla.)
Nov 13, 2024
Magnetic microrobots, designed to navigate the complex environments of the human body, show promise for minimally invasive diagnosis and treatment. However, their clinical adoption faces hurdles such as biocompatibility, precise control, and intellig...
The accurate detection and quantification of rodent behavior forms a cornerstone of basic biomedical research. Current data-driven approaches, which segment free exploratory behavior into clusters, suffer from low statistical power due to multiple te...
Positron emission tomography (PET) utilizes radiotracers like [F]fluorodeoxyglucose (FDG) to measure brain activity in health and disease. Performing behavioral tasks between the FDG injection and the PET scan allows the FDG signal to reflect task-re...
Transcriptomic analyses have advanced the understanding of complex disease pathophysiology including chronic obstructive pulmonary disease (COPD). However, identifying relevant biologic causative factors has been limited by the integration of high di...
Brain-machine interfaces (BMIs) aim to restore sensorimotor function to individuals suffering from neural injury and disease. A critical step in implementing a BMI is to decode movement intention from recorded neural activity patterns in sensorimotor...
Radiation and environmental biophysics
Nov 6, 2024
This study presents a novel approach to skin toxicity assessment in preclinical radiotherapy trials through an advanced imaging setup and deep learning. Skin reactions, commonly associated with undesirable side effects in radiotherapy, were meticulou...
Interferon-gamma (IFN-γ) is a versatile pleiotropic cytokine essential for both innate and adaptive immune responses. It exhibits both pro-inflammatory and anti-inflammatory properties, making it a promising therapeutic candidate for treating various...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nov 6, 2024
Systemic study of pathogenic pathways and interrelationships underlying genes associated with Alzheimer's disease (AD) facilitates the identification of new targets for effective treatments. Recently available large-scale multiomics datasets provide ...
Photon-counting computed tomography (PCCT) reconstructs multiple energy-channel images to describe the same object, where there exists a strong correlation among different channel images. In addition, reconstruction of each channel image suffers phot...
In case-control single-cell RNA-seq studies, sample-level labels are transferred onto individual cells, labeling all case cells as affected, when in reality only a small fraction of them may actually be perturbed. Here, using simulations, we demonstr...
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