Using transcriptomic profiling at single-cell resolution, we investigated cell-intrinsic and cell-extrinsic signatures associated with pathogenesis and inflammation-driven fibrosis in both adult and pediatric patients with localized scleroderma (LS)....
OBJECTIVES: Oral squamous cell carcinoma (OSCC) is the sixth-highest incidence of malignant tumors worldwide. However, early diagnosis is complex owing to the impracticality of biopsying every potentially premalignant intraoral lesion. Here, we prese...
BACKGROUND: T-cell receptor (TCR) repertoires provide insights into tumor immunology, yet their variations across digestive system cancers are not well understood. Characterizing TCR differences between colorectal cancer (CRC) and gastric cancer (GC)...
As a vital tool for human-computer interaction, artificial intelligence (AI) voice assistants have become an integral part of individuals' everyday routines. However, there are still a series of problems caused by privacy violations in current use. T...
International journal of legal medicine
Apr 7, 2025
Bone age assessment (BAA) means challenging tasks in forensic science especially in some extreme situations like only skulls found. This study aimed to develop an accurate three-dimensional deep learning (DL) framework at skull CT metadata for BAA an...
British journal of clinical pharmacology
Apr 7, 2025
AIMS: The incidence of osteoporosis is projected to exceed 70 million people over the age of 65 years by 2030. Osteoanabolic agents, such as teriparatide and abaloparatide, are not only effective in reducing fracture incidence but also improve skelet...
OBJECTIVES: The 2009 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation without race correction factor is frequently used for an estimate of glomerular filtration rate (eGFR) and to support a single-sample GFR regime. This study exa...
AIM: To evaluate a deep learning (DL) model for detecting keratinized gingiva (KG) in dental photographs and validate its clinical applicability using reference retainers for calibration.
BACKGROUND: Migraine is associated with a range of symptoms and comorbid disorders and has a strong genetic basis, but the currently identified risk loci only explain a small portion of the heritability, often termed the "missing heritability". We ai...
Advancements in medical technology have extended long-term electrocardiogram (ECG) monitoring from the traditional 24 h to 7-14 days, significantly enriching ECG data. However, this poses unprecedented challenges for physicians in analyzing these ext...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.