AIMC Topic: Middle East Respiratory Syndrome Coronavirus

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Machine Learning-Guided Screening and Molecular Docking for Proposing Naturally Derived Drug Candidates Against MERS-CoV 3CL Protease.

International journal of molecular sciences Mar 26, 2025
In this study, we utilized machine learning techniques to identify potential inhibitors of the MERS-CoV 3CL protease. Among the models evaluated, the Random Forest (RF) algorithm exhibited the highest predictive performance, achieving an accuracy of ...
Machine Learning Molecular Docking Simulation Drug Discovery Humans Middle East Respiratory Syndrome Coronavirus Protease Inhibitors Antiviral Agents Coronavirus 3C Proteases Molecular Dynamics Simulation Catalytic Domain
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Combining machine learning and nanopore construction creates an artificial intelligence nanopore for coronavirus detection.

Nature communications Jun 17, 2021
High-throughput, high-accuracy detection of emerging viruses allows for the control of disease outbreaks. Currently, reverse transcription-polymerase chain reaction (RT-PCR) is currently the most-widely used technology to diagnose the presence of SAR...
Artificial Intelligence Machine Learning Software Humans Limit of Detection Equipment Design Saliva SARS-CoV-2 Sensitivity and Specificity Nanoparticles Polymerase Chain Reaction Nanopores Middle East Respiratory Syndrome Coronavirus COVID-19 Nucleic Acid Testing Coronavirus 229E, Human
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Evaluation of deep learning approaches for identification of different corona-virus species and time series prediction.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society Apr 23, 2021
Novel corona-virus (nCOV) has been declared as a pandemic that started from the city Wuhan of China. This deadly virus is infecting people rapidly and has targeted 4.93 million people across the world, with 227 K people being infected only in Italy. ...
Pneumonia, Viral Humans COVID-19 SARS-CoV-2 Deep Learning Middle East Respiratory Syndrome Coronavirus Betacoronavirus
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COVID-19 Coronavirus Vaccine Design Using Reverse Vaccinology and Machine Learning.

Frontiers in immunology Jul 3, 2020
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. Our literature and clinical trial survey showed that the whole vi...
Epitopes, B-Lymphocyte SARS-CoV-2 Betacoronavirus Middle East Respiratory Syndrome Coronavirus Animals Pneumonia, Viral Machine Learning Viral Proteins Viral Vaccines Pandemics COVID-19 Vaccines Humans COVID-19 Coronavirus Infections Immunogenicity, Vaccine
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Main factors influencing recovery in MERS Co-V patients using machine learning.

Journal of infection and public health Apr 10, 2019
BACKGROUND: Middle East Respiratory Syndrome (MERS) is a major infectious disease which has affected the Middle Eastern countries, especially the Kingdom of Saudi Arabia (KSA) since 2012. The high mortality rate associated with this disease has been ...
Child Support Vector Machine Regression Analysis Bayes Theorem Coronavirus Infections Multivariate Analysis Humans Saudi Arabia Machine Learning Adolescent Health Personnel Child, Preschool Adult Infant Middle East Respiratory Syndrome Coronavirus Female Male Survival Aged Severity of Illness Index Middle Aged Young Adult
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Large-scale machine learning of media outlets for understanding public reactions to nation-wide viral infection outbreaks.

Methods (San Diego, Calif.) Aug 13, 2017
From May to July 2015, there was a nation-wide outbreak of Middle East respiratory syndrome (MERS) in Korea. MERS is caused by MERS-CoV, an enveloped, positive-sense, single-stranded RNA virus belonging to the family Coronaviridae. Despite expert opi...
Middle East Respiratory Syndrome Coronavirus Humans Machine Learning Mass Media Republic of Korea Disease Outbreaks Coronavirus Infections
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Analyzing the vast coronavirus literature with CoronaCentral.

Proceedings of the National Academy of Sciences of the United States of America Jun 8, 2021
The SARS-CoV-2 pandemic has caused a surge in research exploring all aspects of the virus and its effects on human health. The overwhelming publication rate means that researchers are unable to keep abreast of the literature. To ameliorate this, we p...
Middle East Respiratory Syndrome Coronavirus Severe Acute Respiratory Syndrome Humans Machine Learning Pandemics COVID-19 SARS-CoV-2 Animals
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[Construction and identification of nanobody phage display library targeting Middle East respiratory syndrome coronavirus].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology Dec 1, 2017
Objective To construct a phage display library of specific nano-antibodies against the Middle East respiratory syndrome coronavirus (MERS-CoV) and apply it to the screening of neutralizing nano-antibodies. Methods MERS-CoV receptor-binding domain (RB...
Middle East Respiratory Syndrome Coronavirus Antibodies, Viral Animals Camelids, New World Peptide Library Single-Domain Antibodies
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