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Computational Prediction of Sigma-54 Promoters in Bacterial Genomes by Integrating Motif Finding and Machine Learning Strategies.

IEEE/ACM transactions on computational biology and bioinformatics Mar 15, 2018
Sigma factor, as a unit of RNA polymerase holoenzyme, is a critical factor in the process of gene transcriptional regulation. It recognizes the specific DNA sites and brings the core enzyme of RNA polymerase to the upstream regions of target genes. T...
Genome, Bacterial Amino Acid Motifs DNA-Directed RNA Polymerases RNA Polymerase Sigma 54 Base Sequence False Positive Reactions Promoter Regions, Genetic Transcription, Genetic Machine Learning Software Escherichia coli Models, Statistical Escherichia coli Proteins Reproducibility of Results Computational Biology
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Application of an artificial neural network model for diagnosing type 2 diabetes mellitus and determining the relative importance of risk factors.

Epidemiology and health Mar 10, 2018
OBJECTIVES: To identify the most important demographic risk factors for a diagnosis of type 2 diabetes mellitus (T2DM) using a neural network model.
Diabetes Mellitus, Type 2 Mass Screening Adult Models, Statistical Male Age Distribution Iran Humans Glycated Hemoglobin Middle Aged Neural Networks, Computer Risk Assessment Waist Circumference Female Risk Factors
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Multichannel lung sound analysis for asthma detection.

Computer methods and programs in biomedicine Mar 9, 2018
BACKGROUND AND OBJECTIVE: Lung sound signals convey valuable information of the lung status. Auscultation is an effective technique to appreciate the condition of the respiratory system using lung sound signals. The prior works on asthma detection fr...
Adult Asthma Male Middle Aged Lung Neural Networks, Computer Algorithms Female Signal Processing, Computer-Assisted Young Adult Support Vector Machine Humans Vital Capacity Models, Statistical Predictive Value of Tests Normal Distribution Forced Expiratory Volume Auscultation Respiratory Sounds
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Tissue classification and segmentation of pressure injuries using convolutional neural networks.

Computer methods and programs in biomedicine Mar 3, 2018
BACKGROUND AND OBJECTIVES: This paper presents a new approach for automatic tissue classification in pressure injuries. These wounds are localized skin damages which need frequent diagnosis and treatment. Therefore, a reliable and accurate systems fo...
Sensitivity and Specificity Image Processing, Computer-Assisted Wound Healing Models, Statistical Pressure Ulcer Models, Anatomic Algorithms Necrosis Databases, Factual Humans Wounds and Injuries Tomography, X-Ray Computed Neural Networks, Computer Reproducibility of Results
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Using Big Data Analytics to Advance Precision Radiation Oncology.

International journal of radiation oncology, biology, physics Mar 2, 2018
Big clinical data analytics as a primary component of precision medicine is discussed, identifying where these emerging tools fit in the spectrum of genomics and radiomics research. A learning health system (LHS) is conceptualized that uses clinicall...
Big Data Decision Support Systems, Clinical Genomics Models, Statistical Radiation Oncology Humans Machine Learning Precision Medicine Neoplasms Data Mining Radiotherapy
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The utility of LASSO-based models for real time forecasts of endemic infectious diseases: A cross country comparison.

Journal of biomedical informatics Feb 27, 2018
INTRODUCTION: Accurate and timely prediction for endemic infectious diseases is vital for public health agencies to plan and carry out any control methods at an early stage of disease outbreaks. Climatic variables has been identified as important pre...
Public Health Disease Outbreaks Thailand Incidence Singapore Malaria Japan Models, Statistical Taiwan Algorithms Forecasting Communicable Diseases Reproducibility of Results Humans Machine Learning Infectious Disease Medicine Climate Hand, Foot and Mouth Disease Wavelet Analysis Chickenpox Communicable Disease Control Dengue
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Efficient Embedded Decoding of Neural Network Language Models in a Machine Translation System.

International journal of neural systems Feb 22, 2018
Neural Network Language Models (NNLMs) are a successful approach to Natural Language Processing tasks, such as Machine Translation. We introduce in this work a Statistical Machine Translation (SMT) system which fully integrates NNLMs in the decoding ...
Humans Vocabulary Translating Neural Networks, Computer Models, Statistical Natural Language Processing
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Predicting treatment outcome of drug-susceptible tuberculosis patients using machine-learning models.

Informatics for health & social care Feb 20, 2018
Tuberculosis (TB) is a deadly contagious disease and a serious global health problem. It is curable but due to its lengthy treatment process, a patient is likely to leave the treatment incomplete, leading to a more lethal, drug resistant form of dise...
Interatrial Block Machine Learning Sensitivity and Specificity Treatment Outcome Models, Statistical Tuberculosis Decision Trees Humans Assessment of Medication Adherence Antitubercular Agents Directly Observed Therapy
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Statistical and machine learning approaches to predicting protein-ligand interactions.

Current opinion in structural biology Feb 20, 2018
Data driven computational approaches to predicting protein-ligand binding are currently achieving unprecedented levels of accuracy on held-out test datasets. Up until now, however, this has not led to corresponding breakthroughs in our ability to des...
Ligands Quantitative Structure-Activity Relationship Protein Binding Computational Biology Models, Statistical Proteins Humans Machine Learning Algorithms
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Psoriasis skin biopsy image segmentation using Deep Convolutional Neural Network.

Computer methods and programs in biomedicine Feb 6, 2018
BACKGROUND AND OBJECTIVE: Development of machine assisted tools for automatic analysis of psoriasis skin biopsy image plays an important role in clinical assistance. Development of automatic approach for accurate segmentation of psoriasis skin biopsy...
Support Vector Machine Cluster Analysis Psoriasis Epidermis Humans Models, Statistical Color Neural Networks, Computer Algorithms Biopsy Databases, Factual Skin Reproducibility of Results Dermis Image Processing, Computer-Assisted
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