AIMC Topic: Molecular Imprinting

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Molecularly imprinted polymers for mycotoxin biosensing: Rational design, advanced applications, and future horizons.

Biosensors & bioelectronics
Molecularly imprinted polymers (MIPs) have emerged as transformative synthetic receptors for mycotoxin detection, addressing critical global food safety challenges through their exceptional stability and design flexibility. This review systematically...

Machine Learning-Driven Dual-Recognition Magnetic Imprinted Polymers: Host-Guest/Aptamer Synergy Enabling Ultrasensitive Chloramphenicol Detection.

Analytical chemistry
To address the challenges in detecting chloramphenicol (CAP) in complex food matrices, this study developed a magnetic solid-phase microextraction coupled with a high-performance liquid chromatography (MSPME-HPLC) system that integrates machine learn...

Low-Cost Polyphenol-Polypyrrole Molecularly Imprinted Sensor for Point-of-Care Alzheimer's Detection.

ACS sensors
There is an urgent need for rapid, affordable diagnostics for Alzheimer's disease (AD), particularly those that can detect phosphorylated Tau 181 (p-tau181)─a key biomarker─directly in plasma. We present a scalable, label-free electrochemical biosens...

Ultrasensitive Detection via Machine Learning-Optimized Bacterial-Imprinted Photoelectrochemical Biosensor with Active/Passive Dual-Mode Validation.

Analytical chemistry
Currently, the existing detection platforms face persistent challenges in achieving reliable bacterial identification within complex matrices, particularly in food and environmental specimens, where matrix interference effects substantially compromis...

Research progress on molecularly imprinted polymers (MIPs)-based sensors for the detection of organophosphorus pesticides.

Food chemistry
Organophosphorus pesticides (OPs), widely used in agriculture, have become major focuses of research in food safety and environmental pollution control due to their neurotoxicity and environmental persistence. In recent years, molecularly imprinted p...

Enhancing the Predictive Performance of Molecularly Imprinted Polymer-Based Electrochemical Sensors Using a Stacking Regressor Ensemble of Machine Learning Models.

ACS sensors
The performance of electrochemical sensors is influenced by various factors. To enhance the effectiveness of these sensors, it is crucial to find the right balance among these factors. Researchers and engineers continually explore innovative approach...

Development of surface molecular-imprinted electrochemical sensor for palmitic acid with machine learning assistance.

Talanta
Palmitic acid (PA) is a kind of saturated high fatty acid, which is involved in physiological safety and food quality. A surface molecularly imprinted polymer (MIP) electrochemical sensor was prepared on MXene surface using dopamine (DA) as functiona...

Harnessing Small-Molecule Analyte Detection in Complex Media: Combining Molecularly Imprinted Polymers, Electrolytic Transistors, and Machine Learning.

ACS applied materials & interfaces
Small-molecule analyte detection is key for improving quality of life, particularly in health monitoring through the early detection of diseases. However, detecting specific markers in complex multicomponent media using devices compatible with point-...

Deep learning-assisted smartphone-based molecularly imprinted electrochemiluminescence detection sensing platform: Protable device and visual monitoring furosemide.

Biosensors & bioelectronics
A novel, portable, and smartphone-based molecularly imprinted polymer electrochemiluminescence (MIP-ECL) sensing platform was constructed for sensitive and selective determination of furosemide (FSM). In this platform, MoSe nanoparticles/starch-deriv...

Electrochemical protein recognition based on macromolecular self-assembly of molecularly imprinted polymer: a new strategy to mimic antibody for label-free biosensing.

Journal of materials chemistry. B
A versatile strategy, based on the use of an amphiphilic copolymer as a macromonomer, was developed for the preparation of a fully synthetic MIP (molecularly imprinted polymer) sensor for protein recognition. A UV-crosslinkable copolymer poly(DMA-co-...