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Monte Carlo Method

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Evaluating advanced computing techniques for predicting breeding values in Harnali sheep.

Tropical animal health and production
Advanced computing techniques have been used by animal researchers to understand the intricate data structures for deriving the most reliable allusions of populations in order to conserve genetically superior animals. The present attempt was made to ...

Estimation of drug exposure by machine learning based on simulations from published pharmacokinetic models: The example of tacrolimus.

Pharmacological research
We previously demonstrated that Machine learning (ML) algorithms can accurately estimate drug area under the curve (AUC) of tacrolimus or mycophenolate mofetil (MMF) based on limited information, as well as or even better than maximum a posteriori Ba...

Radiation dose calculation in 3D heterogeneous media using artificial neural networks.

Medical physics
PURPOSE: External beam radiotherapy (EBRT) treatment planning requires a fast and accurate method of calculating the dose delivered by a clinical treatment plan. However, existing methods of calculating dose distributions have limitations. Monte Carl...

Calibrated uncertainty estimation for interpretable proton computed tomography image correction using Bayesian deep learning.

Physics in medicine and biology
Integrated-type proton computed tomography (pCT) measures proton stopping power ratio (SPR) images for proton therapy treatment planning, but its image quality is degraded due to noise and scatter. Although several correction methods have been propos...

DeepDose: a robust deep learning-based dose engine for abdominal tumours in a 1.5 T MRI radiotherapy system.

Physics in medicine and biology
We present a robust deep learning-based framework for dose calculations of abdominal tumours in a 1.5 T MRI radiotherapy system. For a set of patient plans, a convolutional neural network is trained on the dose of individual multi-leaf-collimator seg...

Automatic attenuation map estimation from SPECT data only for brain perfusion scans using convolutional neural networks.

Physics in medicine and biology
In clinical brain SPECT, correction for photon attenuation in the patient is essential to obtain images which provide quantitative information on the regional activity concentration per unit volume (kBq.[Formula: see text]). This correction generally...

Universal probabilistic programming offers a powerful approach to statistical phylogenetics.

Communications biology
Statistical phylogenetic analysis currently relies on complex, dedicated software packages, making it difficult for evolutionary biologists to explore new models and inference strategies. Recent years have seen more generic solutions based on probabi...

A comparison of Monte Carlo dropout and bootstrap aggregation on the performance and uncertainty estimation in radiation therapy dose prediction with deep learning neural networks.

Physics in medicine and biology
Recently, artificial intelligence technologies and algorithms have become a major focus for advancements in treatment planning for radiation therapy. As these are starting to become incorporated into the clinical workflow, a major concern from clinic...

A generative adversarial network approach to (ensemble) weather prediction.

Neural networks : the official journal of the International Neural Network Society
We use a conditional deep convolutional generative adversarial network to predict the geopotential height of the 500 hPa pressure level, the two-meter temperature and the total precipitation for the next 24 h over Europe. The proposed models are trai...

Modeling complex particles phase space with GAN for Monte Carlo SPECT simulations: a proof of concept.

Physics in medicine and biology
A method is proposed to model by a generative adversarial network the distribution of particles exiting a patient during Monte Carlo simulation of emission tomography imaging devices. The resulting compact neural network is then able to generate part...