Optical Monte Carlo (MC) simulations are essential for modeling light transport in radiation detectors used in nuclear imaging and high-energy physics. However, full-system simulations remain computationally prohibitive due to the need to track optic...
Journal of chemical information and modeling
Jun 2, 2025
In the realm of medicinal chemistry, the predominant challenge in molecular design lies in managing extensive molecular data sets and effectively screening for, as well as preserving, molecules with potential value. Traditional methodologies typicall...
During thrombosis, platelets rapidly deposit and activate on the vessel wall, driving conditions such as myocardial infarction and stroke. The complexity of thrombus formation in pathological flow geometries, along with patient-specific pharmacologic...
Simulation-Based Inference (SBI) has recently emerged as a powerful framework for Bayesian inference: Neural networks are trained on simulations from a forward model, and learn to rapidly estimate posterior distributions. We here present an SBI frame...
This work aims to develop and investigate the feasibility of a hybrid model combining Monte Carlo (MC) simulations and deep learning (DL) to predict electronic portal imaging device (EPID) images based on MC-generated exit phase space energy fluence ...
SIGNIFICANCE: Investigating optical properties (OPs) is crucial in the field of biophotonics, as it has a broad impact on understanding light-tissue interactions. However, current techniques, such as inverse Monte Carlo simulations (IMCS), have limit...
. The dose distribution of lung cancer patients treated with the CyberKnife (CK) system is influenced by various factors, including tumor location and the direction of CK beams. The objective of this study is to present a deep learning approach that ...
BACKGROUND: Computed tomography (CT) scans are a major source of medical radiation exposure worldwide. In countries like China, the frequency of CT scans has grown rapidly, thus making available a large volume of organ dose information. With modern c...
BACKGROUND: Conventional proton dose calculation methods are either time- and resource-intensive, like Monte Carlo (MC) simulations, or they sacrifice accuracy, as seen with analytical methods. This trade-off between computational efficiency and accu...
A framework for parameter estimation and uncertainty quantification is crucial for understanding the mechanisms of biological interactions within complex systems and exploring their dynamic behaviors beyond what can be experimentally observed. Despit...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.