AIMC Topic: Monte Carlo Method

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Aleatoric and epistemic uncertainty extraction of patient-specific deep learning-based dose predictions in LDR prostate brachytherapy.

Physics in medicine and biology
In brachytherapy, deep learning (DL) algorithms have shown the capability of predicting 3D dose volumes. The reliability and accuracy of such methodologies remain under scrutiny for prospective clinical applications. This study aims to establish fast...

Deep-Learning for Rapid Estimation of the Out-of-Field Dose in External Beam Photon Radiation Therapy - A Proof of Concept.

International journal of radiation oncology, biology, physics
PURPOSE: The dose deposited outside of the treatment field during external photon beam radiation therapy treatment, also known as out-of-field dose, is the subject of extensive study as it may be associated with a higher risk of developing a second c...

A machine learning approach to predict daptomycin exposure from two concentrations based on Monte Carlo simulations.

Antimicrobial agents and chemotherapy
Daptomycin is a concentration-dependent lipopeptide antibiotic for which exposure/effect relationships have been shown. Machine learning (ML) algorithms, developed to predict the individual exposure to drugs, have shown very good performances in comp...

Optimization of Ganciclovir and Valganciclovir Starting Dose in Children by Machine Learning.

Clinical pharmacokinetics
BACKGROUND AND OBJECTIVES: Ganciclovir (GCV) and valganciclovir (VGCV) show large interindividual pharmacokinetic variability, particularly in children. The objectives of this study were (1) to develop machine learning (ML) algorithms trained on simu...

Monitoring multistage healthcare processes using state space models and a machine learning based framework.

Artificial intelligence in medicine
Monitoring healthcare processes, such as surgical outcomes, with a keen focus on detecting changes and unnatural conditions at an early stage is crucial for healthcare professionals and administrators. In line with this goal, control charts, which ar...

Organ dose prediction for patients undergoing radiotherapy CBCT chest examinations using artificial intelligence.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To propose an artificial intelligence (AI)-based method for personalized and real-time dosimetry for chest CBCT acquisitions.

A physically constrained Monte Carlo-Neural Network coupling algorithm for BNCT dose calculation.

Medical physics
BACKGROUND: In boron neutron capture therapy (BNCT)-a form of binary radiotherapy-the primary challenge in treatment planning systems for dose calculations arises from the time-consuming nature of the Monte Carlo (MC) method. Recent progress, includi...

Numerical stability of DeepGOPlus inference.

PloS one
Convolutional neural networks (CNNs) are currently among the most widely-used deep neural network (DNN) architectures available and achieve state-of-the-art performance for many problems. Originally applied to computer vision tasks, CNNs work well wi...

Designing a use-error robust machine learning model for quantitative analysis of diffuse reflectance spectra.

Journal of biomedical optics
SIGNIFICANCE: Machine learning (ML)-enabled diffuse reflectance spectroscopy (DRS) is increasingly used as an alternative to the computation-intensive inverse Monte Carlo (MCI) simulation to predict tissue's optical properties, including the absorpti...

Deep learning-based synthetic dose-weighted LET map generation for intensity modulated proton therapy.

Physics in medicine and biology
The advantage of proton therapy as compared to photon therapy stems from the Bragg peak effect, which allows protons to deposit most of their energy directly at the tumor while sparing healthy tissue. However, even with such benefits, proton therapy ...