AIMC Topic: Mood Disorders

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Multiple Holdouts With Stability: Improving the Generalizability of Machine Learning Analyses of Brain-Behavior Relationships.

Biological psychiatry
BACKGROUND: In 2009, the National Institute of Mental Health launched the Research Domain Criteria, an attempt to move beyond diagnostic categories and ground psychiatry within neurobiological constructs that combine different levels of measures (e.g...

Decoding rumination: A machine learning approach to a transdiagnostic sample of outpatients with anxiety, mood and psychotic disorders.

Journal of psychiatric research
OBJECTIVE: To employ machine learning algorithms to examine patterns of rumination from RDoC perspective and to determine which variables predict high levels of maladaptive rumination across a transdiagnostic sample.

Personalized prediction of smartphone-based psychotherapeutic micro-intervention success using machine learning.

Journal of affective disorders
BACKGROUND: Tailoring healthcare to patients' individual needs is a central goal of precision medicine. Combining smartphone-based interventions with machine learning approaches may help attaining this goal. The aim of our study was to explore the pr...

Mood Prediction of Patients With Mood Disorders by Machine Learning Using Passive Digital Phenotypes Based on the Circadian Rhythm: Prospective Observational Cohort Study.

Journal of medical Internet research
BACKGROUND: Virtually, all organisms on Earth have their own circadian rhythm, and humans are no exception. Circadian rhythms are associated with various human states, especially mood disorders, and disturbance of the circadian rhythm is known to be ...

Meaningless comparisons lead to false optimism in medical machine learning.

PloS one
A new trend in medicine is the use of algorithms to analyze big datasets, e.g. using everything your phone measures about you for diagnostics or monitoring. However, these algorithms are commonly compared against weak baselines, which may contribute ...

Application of machine learning classification for structural brain MRI in mood disorders: Critical review from a clinical perspective.

Progress in neuro-psychopharmacology & biological psychiatry
Mood disorders are a highly prevalent group of mental disorders causing substantial socioeconomic burden. There are various methodological approaches for identifying the underlying mechanisms of the etiology, symptomatology, and therapeutics of mood ...

Identifying a clinical signature of suicidality among patients with mood disorders: A pilot study using a machine learning approach.

Journal of affective disorders
OBJECTIVE: A growing body of evidence has put forward clinical risk factors associated with patients with mood disorders that attempt suicide. However, what is not known is how to integrate clinical variables into a clinically useful tool in order to...

Construction and verification of risk prediction model for suicidal attempts of mood disorder based on machine learning.

Journal of affective disorders
BACKGROUND: Mood disorders (MD) are closely related to suicide attempt (SA). Developing an effective prediction model for SA in MD patients could play a crucial role in the early identification of high-risk groups.

Personalized prediction of negative affect in individuals with serious mental illness followed using long-term multimodal mobile phenotyping.

Translational psychiatry
Heightened negative affect is a core feature of serious mental illness. Over 90% of American adults own a smartphone, equipped with an array of sensors which can continuously and unobtrusively measure behaviors (e.g., activity levels, location, and p...