Recently developed pathology foundation models, pretrained on large-scale pathology datasets, have demonstrated excellent performance in various downstream tasks. This study evaluated the utility of pathology foundation models combined with multiple ...
Existing multiple instance learning (MIL) methods treat whole slide image (WSI) as collections of independent patches, neglecting these crucial spatial and morphological connections. This paper proposes K-Stage Transformer with multiple instance lear...
Programmed death-ligand 1 (PD-L1) is an important biomarker increasingly used as a predictive marker in breast cancer immunotherapy. Immunohistochemical quantification remains the standard method for assessment. However, it presents challenges relate...
Multiple instance learning (MIL) has been successfully applied for whole slide images (WSIs) analysis in computational pathology, enabling a wide range of prediction tasks from tumor subtyping to inferring genetic mutations and multi-omics biomarkers...
IEEE transactions on bio-medical engineering
Mar 21, 2025
OBJECTIVE: Targeted blood-brain barrier (BBB) opening using focused ultrasound (FUS) and micro/nanobubbles is a promising method for brain drug delivery. This study aims to explore the feasibility of multiple instance learning (MIL) in accurate and f...
Multiple instance learning (MIL) has emerged as a prominent paradigm for processing the whole slide image with pyramid structure and giga-pixel size in digital pathology. However, existing attention-based MIL methods are primarily trained on the imag...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jan 27, 2025
BACKGROUND: Entity-level pathologic structures with independent structures and functions are at a mesoscopic scale between the cell-level and slide-level, containing limited structures thus providing fewer instances for multiple instance learning. Th...
Deep multiple instance learning (MIL) pipelines are the mainstream weakly supervised learning methodologies for whole slide image (WSI) classification. However, it remains unclear how these widely used approaches compare to each other, given the rece...
Colorectal cancer (CRC) is one of the top three most lethal malignancies worldwide, posing a significant threat to human health. Recently proposed immunotherapy checkpoint blockade treatments have proven effective for CRC, but their use depends on me...
Colorectal cancer (CRC) is considered one of the most deadly cancer types nowadays. It is rapidly increasing due to many factors, such as unhealthy lifestyles, water and food pollution, aging, and medical diagnosis development. Detecting CRC in its e...
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