AIMC Topic: Multiple System Atrophy

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Differential diagnosis of multiple system atrophy with predominant parkinsonism and Parkinson's disease using neural networks.

Journal of the neurological sciences Apr 11, 2019
Differential diagnosis between Parkinson's disease (PD) and atypical parkinsonism, such as multiple system atrophy (MSA), can be difficult, especially in the early stages of the disease. Deep learning using neural networks (NNs) makes possible the pr...
Magnetic Resonance Spectroscopy Multiple System Atrophy Diagnosis, Differential Parkinsonian Disorders Humans Aged Male Magnetic Resonance Imaging Neural Networks, Computer Middle Aged Parkinson Disease Deep Learning Pilot Projects Female
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Predictive markers for Parkinson's disease using deep neural nets on neuromelanin sensitive MRI.

NeuroImage. Clinical Mar 6, 2019
Neuromelanin sensitive magnetic resonance imaging (NMS-MRI) has been crucial in identifying abnormalities in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD) as PD is characterized by loss of dopaminergic neurons in the SNc. Curre...
Melanins Multiple System Atrophy Female Supranuclear Palsy, Progressive Sensitivity and Specificity Substantia Nigra Parkinson Disease Humans Neuroimaging Diagnosis, Differential Biomarkers Male Middle Aged Image Processing, Computer-Assisted Deep Learning Magnetic Resonance Imaging
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Automated Imaging Differentiation for Parkinsonism.

JAMA neurology May 1, 2025
IMPORTANCE: Magnetic resonance imaging (MRI) paired with appropriate disease-specific machine learning holds promise for the clinical differentiation of Parkinson disease (PD), multiple system atrophy (MSA) parkinsonian variant, and progressive supra...
Magnetic Resonance Imaging Parkinson Disease Cohort Studies Support Vector Machine Diffusion Magnetic Resonance Imaging Prospective Studies Multiple System Atrophy Humans Male Female Supranuclear Palsy, Progressive Middle Aged Aged Diagnosis, Differential Parkinsonian Disorders
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Extended Technical and Clinical Validation of Deep Learning-Based Brainstem Segmentation for Application in Neurodegenerative Diseases.

Human brain mapping Feb 15, 2025
Disorders of the central nervous system, including neurodegenerative diseases, frequently affect the brainstem and can present with focal atrophy. This study aimed to (1) optimize deep learning-based brainstem segmentation for a wide range of patholo...
Middle Aged Deep Learning Adult Male Multiple Sclerosis Image Interpretation, Computer-Assisted Neuroimaging Magnetic Resonance Imaging Neurodegenerative Diseases Humans Female Reproducibility of Results Aged Cerebral Small Vessel Diseases Brain Stem Multiple System Atrophy
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Differentiation of neurodegenerative parkinsonian syndromes by volumetric magnetic resonance imaging analysis and support vector machine classification.

Movement disorders : official journal of the Movement Disorder Society Oct 1, 2016
BACKGROUND: Clinical differentiation of parkinsonian syndromes is still challenging.
Parkinsonian Disorders Support Vector Machine Multiple System Atrophy Humans Magnetic Resonance Imaging Cerebellar Diseases Supranuclear Palsy, Progressive Brain
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