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Multivariate Analysis

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EEG microstate features for schizophrenia classification.

PloS one
Electroencephalography (EEG) microstate analysis is a method wherein spontaneous EEG activity is segmented at sub-second levels to analyze quasi-stable states. In particular, four archetype microstates and their features are known to reflect changes ...

Integrating deep learning CT-scan model, biological and clinical variables to predict severity of COVID-19 patients.

Nature communications
The SARS-COV-2 pandemic has put pressure on intensive care units, so that identifying predictors of disease severity is a priority. We collect 58 clinical and biological variables, and chest CT scan data, from 1003 coronavirus-infected patients from ...

Quantitative Longitudinal Predictions of Alzheimer's Disease by Multi-Modal Predictive Learning.

Journal of Alzheimer's disease : JAD
BACKGROUND: Quantitatively predicting the progression of Alzheimer's disease (AD) in an individual on a continuous scale, such as the Alzheimer's Disease Assessment Scale-cognitive (ADAS-cog) scores, is informative for a personalized approach as oppo...

Iterative single-cell multi-omic integration using online learning.

Nature biotechnology
Integrating large single-cell gene expression, chromatin accessibility and DNA methylation datasets requires general and scalable computational approaches. Here we describe online integrative non-negative matrix factorization (iNMF), an algorithm for...

Multivariate analysis of Brillouin imaging data by supervised and unsupervised learning.

Journal of biophotonics
Brillouin imaging relies on the reliable extraction of subtle spectral information from hyperspectral datasets. To date, the mainstream practice has been to use line fitting of spectral features to retrieve the average peak shift and linewidth parame...

Profiling of contemporary beer styles using liquid chromatography quadrupole time-of-flight mass spectrometry, multivariate analysis, and machine learning techniques.

Analytica chimica acta
Although all beer is brewed using the same four classes of ingredients, contemporary beer styles show wide variation in flavor and color, suggesting differences in their chemical profiles. A selection of 32 beers covering five styles (India pale ale,...

Prediction of premature all-cause mortality in patients receiving peritoneal dialysis using modified artificial neural networks.

Aging
Premature all-cause mortality is high in patients receiving peritoneal dialysis (PD). The accurate and early prediction of mortality is critical and difficult. Three prediction models, the logistic regression (LR) model, artificial neural network (AN...