AIMC Topic: Nanoparticles

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A Closed-Loop Environmental Health Management Platform: A Multifunctional MgFeO Nanoparticle Enabling AI-Enhanced Detection, Bioimaging, and Degradation of Tetracycline Antibiotics.

Analytical chemistry
Emerging pollutants such as tetracycline antibiotics (TCs) have garnered attention due to their ecological impacts and the evolution of drug resistance. However, the comprehensive monitoring of TCs remains inadequate. This study presents a multifunct...

Machine learning-driven nanoparticle toxicity.

Ecotoxicology and environmental safety
This study presents a comprehensive machine learning-driven analysis to understand and predict the toxicity of nanoparticles (NPs), a crucial aspect in ensuring the safe application of nanotechnology in medicine, pharmaceuticals, biotechnology, and v...

Extracellular vesicles as nature's nano carriers in cancer therapy: Insights toward preclinical studies and clinical applications.

Pharmacological research
Extracellular vesicles (EVs), which are secreted by various cell types, hold significant potential for cancer therapy. However, there are several challenges and difficulties that limit their application in clinical settings. This review, which integr...

Nanotechnology-Enhanced siRNA Delivery: Revolutionizing Cancer Therapy.

ACS applied bio materials
RNA interference (RNAi) has emerged as a transformative approach for cancer therapy, enabling precise gene silencing through small interfering RNA (siRNA). However, the clinical application of siRNA-based treatments faces challenges such as rapid deg...

Machine learning-guided fabrication of carbon dot-pepsin nano-conjugates for enhanced bioimaging, synergistic drug delivery, and visible light-induced photosensitization.

Nanoscale
Carbon dots (CDs) are emerging as next-generation bioimaging agents due to their strong fluorescence, photobleaching resistance, and biocompatibility. However, their small size often limits efficient cell internalization, leading to unspecified cellu...

Exploring nanoparticles in lungs under COPD conditions for nanospray drug flow and deposition: CFD simulations and AI predictions.

International journal of pharmaceutics
Chronic obstructive pulmonary disease (COPD) plays a heavy burden on individuals and the social health system, not only causing direct medical costs but also economic losses. Today, treatments for COPD include drugs, bronchodilators, and oxygen thera...

Unsupervised Adaptive Deep Learning Framework for Video Denoising in Light Scattering Imaging.

Analytical chemistry
Light scattering is a powerful tool that has been widely applied in various scenarios, such as nanoparticle analysis, single-cell measurement, and blood flow monitoring. However, noise is always a concerning and challenging issue in light scattering ...

The Application of Anisotropically Collapsing Gels, Deep Learning, and Optical Microscopy for Chemical Characterization of Nanoparticles and Nanoplastics.

Langmuir : the ACS journal of surfaces and colloids
The surface chemistry of nanomaterials, particularly the density of functional groups, governs their behavior in applications such as bioanalysis, bioimaging, and environmental impact studies. Here, we report a precise method to quantify carboxyl gro...

Exploring therapeutic and diagnostic potential of cysteine cathepsin as targets for cancer therapy with nanomedicine.

International journal of biological macromolecules
Cysteine cathepsins have been discovered to be substantially expressed in multiple types of cancer. They play a key role in the progression and growth of these cancers, rendering them appealing targets for nanoscale delivery and noninvasive diagnosti...

Intelligent deep learning model for targeted cancer drug delivery.

Scientific reports
Nanotechnology and information communication technology (ICT) are being combined to develop innovative drug delivery systems for targeted sites, such as tumor cells. The particulate targeted drug delivery (PTDD) system involves drugs containing nanop...