AIMC Topic: Nanoparticles

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Machine learning integrated with in vitro experiments for study of drug release from PLGA nanoparticles.

Scientific reports
This paper investigates delivery of encapsulated drug from poly lactic-co-glycolic micro-/nano-particles. Experimental data collected from about 50 papers are analyzed by machine learning algorithms including linear regression, principal component an...

Computational biology and artificial intelligence in mRNA vaccine design for cancer immunotherapy.

Frontiers in cellular and infection microbiology
Messenger RNA (mRNA) vaccines offer an adaptable and scalable platform for cancer immunotherapy, requiring optimal design to elicit a robust and targeted immune response. Recent advancements in bioinformatics and artificial intelligence (AI) have sig...

Advancements and Prospects in Nanorobotic Applications for Ophthalmic Therapy.

ACS biomaterials science & engineering
This study provides a bibliometric and bibliographic review of emerging applications of micro- and nanotechnology in treating ocular diseases, with a primary focus on glaucoma. We aim to identify key research trends and analyze advancements in device...

Application of supervised learning models for enhanced lead (II) removal from wastewater via modified cellulose nanocrystals (CNCs).

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
Heavy metal ions are acknowledged to impact the environment and human health adversely. CNCs are effective materials for removing heavy metal ions in industrial applications and process innovations since they can be used in static and dynamic adsorpt...

"Three-in-one" Analysis of Proteinuria for Disease Diagnosis through Multifunctional Nanoparticles and Machine Learning.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Urinalysis is one of the predominant tools for clinical testing owing to the abundant composition, sufficient volume, and non-invasive acquisition of urine. As a critical component of routine urinalysis, urine protein testing measures the levels and ...

Robotic Microcapsule Assemblies with Adaptive Mobility for Targeted Treatment of Rugged Biological Microenvironments.

ACS nano
Microrobots are poised to transform biomedicine by enabling precise, noninvasive procedures. However, current magnetic microrobots, composed of solid monolithic particles, present fundamental challenges in engineering intersubunit interactions, limit...

Kinetics, central composite design and artificial neural network modelling of ciprofloxacin antibiotic photodegradation using fabricated cobalt-doped zinc oxide nanoparticles.

Scientific reports
Cobalt-doped zinc oxide nanoparticles were fabricated and examined in this study as a potential photocatalyst for the antibiotic ciprofloxacin (CIPF) degradation when exposed to visible LED light. The Co-precipitation technique created Cobalt-doped z...

Toward Resolving Heterogeneous Mixtures of Nanocarriers in Drug Delivery Systems through Light Scattering and Machine Learning.

ACS nano
Nanocarriers (NCs) have emerged as a revolutionary approach in targeted drug delivery, promising to enhance drug efficacy and reduce toxicity through precise targeting and controlled release mechanisms. Despite their potential, the clinical adoption ...

Intelligence analysis of drug nanoparticles delivery efficiency to cancer tumor sites using machine learning models.

Scientific reports
This study focuses on the use of machine learning (ML) models to predict the biodistribution of nanoparticles in various organs, using a dataset derived from research on nanoparticle behavior for cancer treatment. The dataset includes both categorica...

Preparation and optimisation of solid lipid nanoparticles of rivaroxaban using artificial neural networks and response surface method.

Journal of microencapsulation
AIMS: This study aimed to improve rivaroxaban delivery by optimising solid lipid nanoparticles (SLN) for minimal mean diameter and maximal entrapment efficiency (EE), enhancing solubility, bioavailability, and the ability to cross the blood-brain bar...